Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | POLB | P06746 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.65 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | BLM | P54132 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | HPGD | P15428 | 5/20 | 0.53 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.53 |
| ▸ | CLK1 | P49759 | 1/20 | 0.53 |
| ▸ | CLK2 | P49760 | 1/20 | 0.53 |
| ▸ | CLK3 | P49761 | 1/20 | 0.53 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.53 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.53 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.53 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.53 |
| ▸ | CDK9 | P50750 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30083760 | 1.00 | KDM4E (0.65) | KDM4EMEN1KMT2APOLBMAPT | |
| Hydrochloric Acid SCHEMBL29388257 | 0.99 | KDM4E (0.63) | KDM4EMEN1KMT2APOLBMAPT | |
| SCHEMBL31738495 | 0.87 | KDM4E (0.66) | KDM4EMEN1KMT2APOLBMAPT | |
| SCHEMBL8790775 | 0.87 | KDM4E (0.66) | KDM4EMEN1KMT2APOLBMAPT | |
| SCHEMBL9550649 | 0.81 | ALOX15 (0.51) | KDM4EMEN1KMT2APOLBMAPT | |
| SCHEMBL11741686 | 0.79 | KDM4E (0.63) | KDM4EMEN1KMT2APOLBMAPT | |
| SCHEMBL3696223 | 0.79 | MEN1 (0.58) | KDM4EMEN1KMT2APOLBMAPT | |
| SCHEMBL9550651 | 0.78 | ALOX15 (0.48) | DYRK1ACDK5CLK4DYRK1BHSD17B10 | |
| SCHEMBL19302622 | 0.77 | KDM4E (0.69) | KDM4EMEN1KMT2APOLBMAPT | |
| Butyric Acid SCHEMBL29284801 | 0.77 | KDM4E (0.45) | KDM4EMEN1KMT2APOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0569380-A1 | ACRIDINE DERIVATIVES. | GLAXO LAB SA (FR) | 1993-11-18 | — | — | EP | claimed |
| WO-1992012132-A1 | ACRIDINE DERIVATIVES | LABORATOIRES GLAXO S.A. (FR) | 1992-07-23 | — | — | WO | claimed |
| EP-0569380-A1 | ACRIDINE DERIVATIVES. | GLAXO LAB SA (FR) | 1993-11-18 | — | — | EP | disclosed |
| WO-1992012132-A1 | ACRIDINE DERIVATIVES | LABORATOIRES GLAXO S.A. (FR) | 1992-07-23 | — | — | WO | disclosed |