Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | PBRM1 | Q86U86 | 2/20 | 0.48 |
| ▸ | FEN1 | P39748 | 1/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.42 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | MPO | P05164 | 3/20 | 0.40 |
| ▸ | GUSB | P08236 | 4/20 | 0.40 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.40 |
| ▸ | PLK4 | O00444 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | RET | P07949 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7568778 | 0.86 | PBRM1 (0.65) | PBRM1FEN1DYRK1APARP1GUSB | |
| SCHEMBL9550649 | 0.81 | ALOX15 (0.51) | ALOX15MAPK1CASP1CASP7HSD17B10 | |
| SCHEMBL4960238 | 0.79 | PBRM1 (0.74) | ALOX15MAPK1CASP1CASP7HSD17B10 | |
| SCHEMBL9550632 | 0.78 | KDM4E (0.65) | ALOX15MAPK1CASP1CASP7HSD17B10 | |
| SCHEMBL30083760 | 0.78 | KDM4E (0.65) | ALOX15MAPK1CASP1CASP7HSD17B10 | |
| Hydrochloric Acid SCHEMBL6206962 | 0.77 | GUSB (0.59) | GUSBRAB9A | |
| Hydrochloric Acid SCHEMBL29388257 | 0.77 | KDM4E (0.63) | ALOX15MAPK1CASP1CASP7HSD17B10 | |
| SCHEMBL30909242 | 0.72 | MPO (0.57) | MPOGUSBRAB9A | |
| SCHEMBL28510989 | 0.72 | PARP1 (0.59) | ALOX15MAPK1CASP1CASP7HSD17B10 | |
| SCHEMBL8790055 | 0.72 | PBRM1 (0.63) | PBRM1FEN1DYRK1APARP1AURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0569380-A1 | ACRIDINE DERIVATIVES. | GLAXO LAB SA (FR) | 1993-11-18 | — | — | EP | disclosed |
| WO-1992012132-A1 | ACRIDINE DERIVATIVES | LABORATOIRES GLAXO S.A. (FR) | 1992-07-23 | — | — | WO | disclosed |