Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.36 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24727444 | 0.71 | AHR (0.43) | AHRKDM4EKIF11MAPTTSHR | |
| SCHEMBL22180535 | 0.68 | FEN1 (0.43) | KDM4ECCNB2CDK1CCNB1CDK5 | |
| Formic Acid Methyl Ester SCHEMBL28113321 | 0.67 | MAPT (0.54) | KDM4EMAPTALDH1A1ALOX15 | |
| SCHEMBL6926709 | 0.67 | DYRK1A (0.68) | AHRKDM4EKIF11MAPTKMT2A | |
| SCHEMBL13560649 | 0.66 | KIF11 (0.56) | AHRCHEK1KDM4EKIF11MAPT | |
| SCHEMBL14115028 | 0.66 | GFER (0.55) | AHRKDM4EKIF11MAPTMAPK10 | |
| SCHEMBL14116119 | 0.66 | KIF11 (0.72) | AHRKDM4EKIF11MAPTKMT2A | |
| SCHEMBL454277 | 0.66 | HTR2A (0.43) | AHRKDM4EKMT2AALDH1A1MEN1 | |
| SCHEMBL26246971 | 0.66 | GFER (0.59) | AHRKDM4EKIF11MAPTMAPK10 | |
| SCHEMBL28672386 | 0.66 | ERCC5 (0.44) | AHRKDM4EMAPTTSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0569380-A1 | ACRIDINE DERIVATIVES. | GLAXO LAB SA (FR) | 1993-11-18 | — | — | EP | disclosed |
| WO-1992012132-A1 | ACRIDINE DERIVATIVES | LABORATOIRES GLAXO S.A. (FR) | 1992-07-23 | — | — | WO | disclosed |