Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNASE1 | P07998 | 1/20 | 0.52 |
| ▸ | TOP2A | P11388 | 4/20 | 0.52 |
| ▸ | TK1 | P04183 | 6/20 | 0.50 |
| ▸ | TK2 | O00142 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9550739 | 1.00 | RNASE1 (0.52) | RNASE1TOP2ATK1TK2 | |
| SCHEMBL8742397 | 0.93 | TOP2A (0.48) | RNASE1TOP2ATK1TK2 | |
| SCHEMBL8659584 | 0.93 | TOP2A (0.48) | RNASE1TOP2ATK1TK2 | |
| SCHEMBL9324697 | 0.88 | RNASE1 (0.58) | RNASE1TK1TK2 | |
| SCHEMBL24059189 | 0.87 | TOP2A (0.54) | RNASE1TOP2ATK1 | |
| SCHEMBL6827410 | 0.85 | TOP2A (0.52) | RNASE1TOP2ATK1 | |
| SCHEMBL12762676 | 0.85 | TOP2A (0.65) | RNASE1TOP2ATK1 | |
| SCHEMBL21563908 | 0.85 | TOP2A (0.65) | RNASE1TOP2ATK1 | |
| SCHEMBL1514947 | 0.85 | TOP2A (0.65) | RNASE1TOP2ATK1 | |
| SCHEMBL24059082 | 0.85 | TOP2A (0.55) | RNASE1TOP2ATK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0558749-A1 | ANTISENSE NUCLEIC ACID DERIVATIVE | SANKYO COMPANY LIMITED (JP) | 1993-09-08 | — | — | EP | disclosed |