SCHEMBL9324697

SCHEMBL9324697

Cc1cn([C@@H]2C[C@@H](OCc3ccccc3)[C@@H](COCc3ccccc3)O2)c(=O)[nH]c1=O

nearest known ligand 0.80

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
RNASE1 P07998 1/20 0.58
TK1 P04183 8/20 0.56
TK2 O00142 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9755168 0.90 TK1 (0.47) RNASE1TK1TK2
SCHEMBL6323252 0.89 RNASE1 (0.59) RNASE1TK1TK2
SCHEMBL8374922 0.89 RNASE1 (0.59) RNASE1TK1TK2
SCHEMBL31355237 0.89 RNASE1 (0.72) RNASE1TK1TK2
SCHEMBL9550739 0.88 RNASE1 (0.52) RNASE1TK1TK2
SCHEMBL9550741 0.88 RNASE1 (0.52) RNASE1TK1TK2
SCHEMBL9550743 0.88 TK1 (0.64) TK1
SCHEMBL8527785 0.88 TK1 (0.64) TK1
SCHEMBL12718428 0.85 RNASE1 (0.67) RNASE1TK1TK2
SCHEMBL11031554 0.84 LMNA (0.49) RNASE1TK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0301908-B1 1-(3,5-Di-0-benzoyl-2-deoxy-beta-D-threo-pentofuranosyl)thymine and the method of producing the same CESKOSLOVENSKA AKADEMIE VED (CS) 1994-02-09 EP disclosed