Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.69 |
| ▸ | HTT | P42858 | 2/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | ERN1 | O75460 | 8/20 | 0.59 |
| ▸ | GPR35 | Q9HC97 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12492120 | 0.87 | ERN1 (0.69) | MEN1KMT2AHTTLMNAERN1 | |
| SCHEMBL205059 | 0.82 | MEN1 (1.00) | MEN1KMT2AHTTLMNAERN1 | |
| SCHEMBL4756022 | 0.81 | ERN1 (0.63) | MEN1KMT2AHTTLMNAERN1 | |
| SCHEMBL12095462 | 0.81 | MEN1 (0.95) | MEN1KMT2AHTTLMNAERN1 | |
| SCHEMBL29441809 | 0.80 | ERN1 (0.67) | MEN1KMT2AERN1GPR35ALDH1A1 | |
| SCHEMBL831073 | 0.80 | ERN1 (0.67) | MEN1KMT2AERN1GPR35ALDH1A1 | |
| SCHEMBL1300813 | 0.79 | ERN1 (0.59) | MEN1KMT2AHTTLMNAERN1 | |
| SCHEMBL6152768 | 0.79 | ERN1 (0.64) | MEN1KMT2AHTTLMNAERN1 | |
| SCHEMBL8169950 | 0.79 | ERN1 (0.59) | MEN1KMT2AHTTLMNAERN1 | |
| SCHEMBL1301289 | 0.79 | GPR35 (0.61) | MEN1KMT2AHTTLMNAERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105440029-A | 5-(1,2,4-Triazol-1-yl)-2-benzylaminothiazole derivatives and application thereof as antitumor drug | UNIV HUNAN | 2016-03-30 | — | — | CN | disclosed |
| CN-104557901-A | 5-(1,2,4-triazole-1-yl)-2-benzylamino thiazole derivative and application thereof as bactericide | HUNAN RES INST OF CHEMICAL INDUSTRY CO LTD | 2015-04-29 | — | — | CN | disclosed |
| US-5230986-A | Photohardening compositions with free radical polymerizable compounds | STEREOGRAPHICS LIMITED PARTNERSHIP (US) | 1993-07-27 | — | — | US | disclosed |