Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 5/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | TTR | P02766 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | XDH | P47989 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12492120 | 0.90 | ERN1 (0.69) | ERN1MEN1KMT2AGPR35KDM4E | |
| SCHEMBL8169950 | 0.85 | ERN1 (0.59) | ERN1MEN1KMT2AGPR35KDM4E | |
| SCHEMBL13196183 | 0.83 | GPR35 (0.56) | ERN1MEN1KMT2AGPR35KDM4E | |
| SCHEMBL16838207 | 0.83 | ERN1 (0.61) | ERN1MEN1KMT2AGPR35KDM4E | |
| SCHEMBL831073 | 0.83 | ERN1 (0.67) | ERN1MEN1KMT2AGPR35KDM4E | |
| SCHEMBL29441809 | 0.83 | ERN1 (0.67) | ERN1MEN1KMT2AGPR35KDM4E | |
| SCHEMBL6152768 | 0.81 | ERN1 (0.64) | ERN1MEN1KMT2AGPR35KDM4E | |
| SCHEMBL1301289 | 0.81 | GPR35 (0.61) | ERN1MEN1KMT2AGPR35ALDH1A1 | |
| SCHEMBL9550826 | 0.81 | MEN1 (0.69) | ERN1MEN1KMT2AGPR35KDM4E | |
| SCHEMBL1300813 | 0.81 | ERN1 (0.59) | ERN1MEN1KMT2AGPR35KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119505155-A | Method for preparing photosensitive polyion liquid photoelectric device by dispensing | 四川大学 | 2025-02-25 | — | — | CN | claimed |
| CN-110105579-B | Intracellular tracing carrier with main chain containing spiropyran as well as preparation and application thereof | 四川大学 | 2020-06-30 | — | — | CN | claimed |
| CN-105237437-B | Entacapone impurity compound and preparation method thereof | 重庆植恩药业有限公司 | 2017-05-17 | — | — | CN | claimed |
| CN-105237437-A | Entacapone impurity compound and preparation method thereof | CHONGQING ZHIEN PHARMACEUTICAL CO LTD | 2016-01-13 | — | — | CN | claimed |
| CN-104402764-A | Preparation method for entacapone | CHEER FINE PHARMACEUTICAL ANHUI CO LTD | 2015-03-11 | — | — | CN | claimed |
| CN-100999473-A | 5-nitro coffeic acid phenylglycollic ester and its preparation and use | UNIV ZHEJIANG TECHNOLOGY (CN) | 2007-07-18 | — | — | CN | claimed |
| EP-1713768-A2 | NOVEL CRYSTALLINE FORMS OF ENTACAPONE AND PRODUCTION THEREOF | Cilag AG (CH) | 2006-10-25 | — | — | EP | claimed |
| WO-2005063695-A1 | NOVEL CRYSTALLINE FORMS OF ENTACAPONE, AND PRODUCTION THEREOF | CILAG AG (CH) | 2005-07-14 | — | — | WO | claimed |
| WO-2005063696-A2 | NOVEL CRYSTALLINE FORMS OF ENTACAPONE AND PRODUCTION THEREOF | CILAG AG (CH) | 2005-07-14 | — | — | WO | claimed |
| CN-1064673-C | New method for preparation of 3,4-dihydroxy-5-nitrobenzaldehyde | ORION YHTYMAE OY (FI) | 2001-04-18 | — | — | CN | claimed |
| CN-1164852-A | New preparation method of 3, 4-dihydroxy-5-nitrobenzaldehyde | ORION YHTYMAE OY (FI) | 1997-11-12 | — | — | CN | claimed |
| CN-119505155-A | Method for preparing photosensitive polyion liquid photoelectric device by dispensing | 四川大学 | 2025-02-25 | — | — | CN | disclosed |
| US-20250051348-A1 | MECHANOPHORIC MATRICES AND METHODS OF PREPARING SAME | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) | 2025-02-13 | — | — | US | disclosed |
| WO-2024200864-A1 | METHOD FOR THE SYNTHETIC CLEANING OF PEPTIDES WITHOUT HPLC | Technische Universität Berlin (DE) | 2024-10-03 | — | — | WO | disclosed |
| CN-117447636-A | Photo/mechanochromatic material and preparation method and application thereof | 中国科学技术大学 | 2024-01-26 | — | — | CN | disclosed |
| US-5389653-A | Inhibitors of the enzyme catechol-O-methyltransferase; useful as co-medication in treatment of Parkinson's disease | HOFFMAN-LA ROCHE INC. (US) | 1995-02-14 | — | — | US | disclosed |
| US-5236952-A | Inhibit the enzyme catechol-O-methyltransferase; for treatment of Parkinson's disease administered with L-dopa | HOFFMANN-LA ROCHE INC. (US) | 1993-08-17 | — | — | US | disclosed |
| EP-0237929-B1 | 3,5-DISUBSTITUTED PYROCATECHOL DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1993-06-02 | — | — | EP | disclosed |
| CN-87108011-A | New compounds with pharmacological activity, preparation method and related components thereof | ORION YHTYMAE OY (FI) | 1988-06-08 | — | — | CN | disclosed |
| EP-0237929-A1 | 3,5-Disubstituted pyrocatechol derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1987-09-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250051348-A1 | MECHANOPHORIC MATRICES AND METHODS OF PREPARING SAME | COL2A1, PIEZO1, MB | ERN1 4276/4885MEN1 163/4885KMT2A 3541/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.