Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.43 |
| ▸ | CCR8 | P51685 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 2/20 | 0.42 |
| ▸ | TGFBR1 | P36897 | 6/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9500899 | 0.88 | BRD4 (0.41) | CCR1CCR8GRM5TGFBR1BRD4 | |
| SCHEMBL9026506 | 0.82 | KCNH2 (0.39) | BRD4SMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL6084743 | 0.81 | NPC1 (0.55) | CCR1CCR8GRM5SMN1; SMN2ALDH1A1 | |
| SCHEMBL9676340 | 0.78 | LMNA (0.43) | CCR1CCR8TGFBR1BRD4MAPK14 | |
| SCHEMBL19630564 | 0.78 | SMN1; SMN2 (0.44) | GRM5TGFBR1BRD4SMN1; SMN2ALDH1A1 | |
| SCHEMBL15470589 | 0.77 | CCR1 (0.60) | CCR1CCR8GRM5TGFBR1MAPK14 | |
| SCHEMBL1563589 | 0.77 | SMN1; SMN2 (0.56) | CCR1CCR8GRM5BRD4SMN1; SMN2 | |
| SCHEMBL10539132 | 0.76 | CYP2A6 (0.53) | CCR1CCR8GRM5TGFBR1MAPK14 | |
| SCHEMBL9027236 | 0.76 | FFAR1 (0.40) | GRM5TGFBR1BRD4NPC1RAB9A | |
| SCHEMBL9678508 | 0.76 | POLB (0.43) | CCR1CCR8GRM5TGFBR1BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5213878-A | — | — | None | — | — | JP | disclosed |
| JP-H05213878-A | NITROGEN-CONTAINING HETEROCYCLIC DERIVATIVE AND GERMICIDE FOR AGRICULTURE AND HORTICULTURE | NIPPON SODA CO LTD | 1993-08-24 | — | — | JP | disclosed |
| EP-0518862-A1 | PYRIMIDINE DERIVATIVES, PROCESS FOR MAKING THEM, AGENTS CONTAINING THEM AND THEIR USE AS FUNGICIDES | Hoechst Schering AgrEvo GmbH (DE) | 1992-12-23 | — | — | EP | disclosed |
| WO-1991007400-A1 | PYRIMIDINE DERIVATIVES, PROCESS FOR MAKING THEM, AGENTS CONTAINING THEM AND THEIR USE AS FUNGICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-05-30 | — | — | WO | disclosed |
| CN-1051559-A | Pyrimidine derivatives, its preparation method contains the preparation of these pyrimidine derivatives and they application as sterilant | HOECHST AG (DE) | 1991-05-22 | — | — | CN | disclosed |