Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CCR1 | P32246 | 1/20 | 0.35 |
| ▸ | CCR8 | P51685 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9550832 | 0.88 | CCR1 (0.43) | BRD4SMN1; SMN2NPC1ALDH1A1RAB9A | |
| SCHEMBL9025837 | 0.87 | GRM5 (0.43) | SMN1; SMN2RAB9AFFAR1GRM5 | |
| SCHEMBL9027236 | 0.87 | FFAR1 (0.40) | BRD4NPC1RAB9AFFAR1GRM5 | |
| SCHEMBL9025927 | 0.83 | GRM5 (0.38) | FFAR1GRM5CCR1CCR8 | |
| SCHEMBL9026730 | 0.82 | ROCK1 (0.43) | RAB9AGRM5 | |
| SCHEMBL9026506 | 0.82 | KCNH2 (0.39) | BRD4SMN1; SMN2NPC1ALDH1A1RAB9A | |
| SCHEMBL9024906 | 0.81 | GRM5 (0.44) | SMN1; SMN2NPC1ALDH1A1FFAR1GRM5 | |
| SCHEMBL10368628 | 0.79 | GRM5 (0.39) | ALDH1A1FFAR1GRM5TGFBR1CCR1 | |
| SCHEMBL9026091 | 0.79 | FFAR1 (0.44) | BRD4ALDH1A1FFAR1GRM5 | |
| SCHEMBL9027654 | 0.78 | BRD4 (0.45) | BRD4SMN1; SMN2NPC1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5117264-A | — | — | None | — | — | JP | disclosed |
| JP-H05117264-A | PYRIDYLPYRIMIDINE COMPOUND, ITS PRODUCTION AND FUNGICIDAL COMPOSITION CONTAINING THE SAME | IMPERIAL CHEM IND PLC <ICI> | 1993-05-14 | — | — | JP | disclosed |
| US-5185339-A | FUNGICIDAL COMPOUNDS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-02-09 | — | — | US | disclosed |
| EP-0459662-A1 | Fungicidal compounds | ZENECA LIMITED (GB) | 1991-12-04 | — | — | EP | disclosed |