Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 14/20 | 1.00 |
| ▸ | PDE3A | Q14432 | 10/20 | 1.00 |
| ▸ | PDE3B | Q13370 | 9/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 4/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 4/20 | 1.00 |
| ▸ | LMNA | P02545 | 3/20 | 1.00 |
| ▸ | USP2 | O75604 | 2/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 1.00 |
| ▸ | HIF1A | Q16665 | 2/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 2/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 2/20 | 1.00 |
| ▸ | TSHR | P16473 | 2/20 | 1.00 |
| ▸ | PDE4A | P27815 | 2/20 | 1.00 |
| ▸ | KCNH2 | Q12809 | 2/20 | 1.00 |
| ▸ | PDE4D | Q08499 | 2/20 | 1.00 |
| ▸ | PDE2A | O00408 | 1/20 | 1.00 |
| ▸ | ABCC4 | O15439 | 1/20 | 1.00 |
| ▸ | PDE5A | O76074 | 1/20 | 1.00 |
| ▸ | ABCB11 | O95342 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Papaverine SCHEMBL29387160 | 1.00 | PDE10A (1.00) | PDE10APDE3APDE3BSMN1; SMN2CYP3A4 | |
| Papaverine SCHEMBL34702 | 1.00 | PDE10A (1.00) | PDE10APDE3APDE3BSMN1; SMN2CYP3A4 | |
| Papaverine SCHEMBL29360983 | 1.00 | PDE10A (1.00) | PDE10APDE3APDE3BSMN1; SMN2CYP3A4 | |
| Papaverine SCHEMBL28169527 | 0.99 | PDE10A (0.97) | PDE10APDE3APDE3BSMN1; SMN2CYP3A4 | |
| Papaverine SCHEMBL29696479 | 0.99 | PDE10A (1.00) | PDE10APDE3APDE3BSMN1; SMN2CYP3A4 | |
| Papaverine SCHEMBL8691148 | 0.99 | PDE10A (0.97) | PDE10APDE3APDE3BSMN1; SMN2CYP3A4 | |
| Papaverine SCHEMBL677440 | 0.99 | PDE10A (0.97) | PDE10APDE3APDE3BSMN1; SMN2CYP3A4 | |
| Papaverine SCHEMBL29356374 | 0.99 | PDE10A (1.00) | PDE10APDE3APDE3BSMN1; SMN2CYP3A4 | |
| Papaverine SCHEMBL9614479 | 0.99 | PDE10A (1.00) | PDE10APDE3APDE3BSMN1; SMN2CYP3A4 | |
| Papaverine SCHEMBL5500363 | 0.99 | PDE10A (1.00) | PDE10APDE3APDE3BSMN1; SMN2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101398414-B | Method for qualitatively screening 242 kinds of compounds by liquid phase chromatography-mass spectra at the same times | CRIMINAL INVEST DEPT OF SHANGHAI POLICE STATION | 2011-07-20 | — | — | CN | disclosed |
| CN-101398414-A | Method for qualitatively screening 242 kinds of compounds by liquid phase chromatography-mass spectra at the same times | CRIMINAL INVEST GENERAL UNIT O (CN) | 2009-04-01 | — | — | CN | disclosed |
| US-5256652-A | Administering peripheral vasodilator and hydroxy-B-cyclo-dextrin to enhance erection | PHARMEDIC CO. (US) | 1993-10-26 | — | — | US | disclosed |
| US-4849412-A | PAPAVERINE COMPOUND, NUCLEOSIDE ANALOG | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1989-07-18 | — | — | US | disclosed |
| US-4800081-A | CALCIUM INFLUX BLOCKER SYNERGISTIC WITH INTERFERON OR CYCLIC NUCLEOTIDE MODULATOR | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1989-01-24 | — | — | US | disclosed |