Papaverine

Papaverine

SCHEMBL29360983

COc1ccc(Cc2nccc3cc(OC)c(OC)cc23)cc1OC

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE10A Q9Y233 14/20 1.00
PDE3A Q14432 10/20 1.00
PDE3B Q13370 9/20 1.00
SMN1; SMN2 Q16637 5/20 1.00
CYP3A4 P08684 4/20 1.00
MAPK1 P28482 4/20 1.00
LMNA P02545 3/20 1.00
USP2 O75604 2/20 1.00
ALDH1A1 P00352 2/20 1.00
HIF1A Q16665 2/20 1.00
CYP1A2 P05177 2/20 1.00
CYP2C9 P11712 2/20 1.00
TSHR P16473 2/20 1.00
PDE4A P27815 2/20 1.00
KCNH2 Q12809 2/20 1.00
PDE4D Q08499 2/20 1.00
PDE2A O00408 1/20 1.00
ABCC4 O15439 1/20 1.00
PDE5A O76074 1/20 1.00
ABCB11 O95342 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Papaverine SCHEMBL29387160 1.00 PDE10A (1.00) PDE10APDE3APDE3BSMN1; SMN2CYP3A4
Papaverine SCHEMBL34702 1.00 PDE10A (1.00) PDE10APDE3APDE3BSMN1; SMN2CYP3A4
Papaverine SCHEMBL9551009 1.00 PDE10A (1.00) PDE10APDE3APDE3BSMN1; SMN2CYP3A4
Papaverine SCHEMBL28169527 0.99 PDE10A (0.97) PDE10APDE3APDE3BSMN1; SMN2CYP3A4
Papaverine SCHEMBL29696479 0.99 PDE10A (1.00) PDE10APDE3APDE3BSMN1; SMN2CYP3A4
Papaverine SCHEMBL8691148 0.99 PDE10A (0.97) PDE10APDE3APDE3BSMN1; SMN2CYP3A4
Papaverine SCHEMBL677440 0.99 PDE10A (0.97) PDE10APDE3APDE3BSMN1; SMN2CYP3A4
Papaverine SCHEMBL29356374 0.99 PDE10A (1.00) PDE10APDE3APDE3BSMN1; SMN2CYP3A4
Papaverine SCHEMBL9614479 0.99 PDE10A (1.00) PDE10APDE3APDE3BSMN1; SMN2CYP3A4
Papaverine SCHEMBL5500363 0.99 PDE10A (1.00) PDE10APDE3APDE3BSMN1; SMN2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 284 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119144726-A Method for improving tumor detection sensitivity through gene methylation signal pre-amplification 昆明市延安医院(昆明市干部疗养院) 2024-12-17 CN claimed
CN-116859404-A Moon laser ranging system 中国科学院云南天文台 2023-10-10 CN claimed
CN-115135669-B Modified Fc region 硕腾服务有限责任公司 2026-05-19 CN disclosed
WO-2026098549-A1 METHOD EXECUTED BY USER EQUIPMENT, AND USER EQUIPMENT 夏普株式会社 2026-05-15 WO disclosed
EP-3129065-B1 TARGETED DRUG DELIVERY THROUGH AFFINITY BASED LINKERS AKAMARA THERAPEUTICS INC (US) 2026-05-13 EP disclosed
US-20260116997-A1 METHODS AND COMPOSITIONS FOR TREATING MMP-9 MEDIATED DISORDERS ASHIBIO INC (US) 2026-04-30 US disclosed
US-20260110013-A1 PROCESS FOR MANIPULATING THE LEVEL OF GLYCAN CONTENT OF A GLYCOPROTEIN AMGEN INC. (US) 2026-04-23 US disclosed
EP-3719122-B1 SIALYLATED GLYCOPROTEINS MOMENTA PHARMACEUTICALS INC (US) 2026-04-01 EP disclosed
EP-4709760-A2 HIGH CONCENTRATION FORMULATIONS FOR MONOCLONAL ANTIBODIES Icahn School of Medicine at Mount Sinai (US) 2026-03-18 EP disclosed
EP-4707306-A2 ANTIBODIES TO PLASMINOGEN ACTIVATOR INHIBITOR-1 (PAI-1) AND USES THEREOF Sanofi (FR) 2026-03-11 EP disclosed
EP-4704703-A1 METHODS AND SYSTEMS FOR TRANSLATION OF NEURAL ACTIVITY INTO EMBODIED DIGITAL-AVATAR ANIMATION The Regents of University of California (US) 2026-03-11 EP disclosed
CN-114206316-A Excipients for biotherapeutics 慕尼黑路德维希-马克西米利安斯大学 2022-03-18 CN disclosed
US-20220079502-A1 DEVICES AND METHODS FOR REMOTE THERAPY AND PATIENT MONITORING AVENUE VENTURE OPPORTUNITIES FUND II, L.P. 2022-03-17 US disclosed
CN-114181312-A Galactose engineered immunoglobulin 1 antibodies 豪夫迈·罗氏有限公司 2022-03-15 CN disclosed
US-20220076080-A1 System and a Method for Assessment of Robustness and Fairness of Artificial Intelligence (AI) Based Models B.G. NEGEV TECHNOLOGIES AND APPLICATIONS LTD., AT BEN-GURION UNIVERSITY (IL) 2022-03-10 US disclosed
US-20220056109-A1 GLYCOPROTEINS WITH ANTI-INFLAMMATORY PROPERTIES MOMENTA PHARMACEUTICALS, INC. 2022-02-24 US disclosed
US-11244698-B2 Systems and methods for identifying human emotions and/or mental health states based on analyses of audio inputs and/or behavioral data collected from computing devices COGITO CORPORATION (US) 2022-02-08 US disclosed
WO-2022023528-A1 CYTOSOLIC DELIVERY THE FRANCIS CRICK INSTITUTE LIMITED (GB) 2022-02-03 WO disclosed
US-11236159-B2 Methods of treating FGF21-associated disorders NOVARTIS AG (CH) 2022-02-01 US disclosed
WO-2022016260-A1 METHODS AND SYSTEMS FOR DIGITAL IMAGE-REFERENCED INDIRECT TARGET AIMING KWESST, INC. (CA) 2022-01-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260116997-A1 METHODS AND COMPOSITIONS FOR TREATING MMP-9 MEDIATED DISORDERS MMP9, MMP11, MMP10 PDE10A 1976/4885PDE3A 1819/4885PDE3B 2082/4885
US-20260110013-A1 PROCESS FOR MANIPULATING THE LEVEL OF GLYCAN CONTENT OF A GLYCOPROTEIN FUCA2, FUCA1, GOLIM4 PDE10A 4795/4885PDE3A 4875/4885PDE3B 4877/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.