SCHEMBL9551340

CC(C)[C@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](N)CCCNC(=N)N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 7)

	gene	UniProt	supporting neighbours	confidence
▸	IL23R	Q5VWK5	13/20	0.55

▸	ERAP2	Q6P179	1/20	0.52

▸	RXFP1	Q9HBX9	1/20	0.51

▸	GHSR	Q92847	3/20	0.51

▸	NPY2R	P49146	1/20	0.51

▸	CD47	Q08722	1/20	0.50

▸	PRMT1	Q99873	1/20	0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL9551338	0.96	IL23R (0.57)	IL23RRXFP1GHSRNPY2R
SCHEMBL9551263	0.96	IL23R (0.58)	IL23RGHSRNPY2RCD47PRMT1
SCHEMBL30130526	0.94	IL23R (0.55)	IL23RGHSRCD47PRMT1
SCHEMBL30130542	0.94	IL23R (0.55)	IL23RGHSRCD47PRMT1
SCHEMBL30093017	0.94	GHSR (0.55)	IL23RGHSRCD47
SCHEMBL30092977	0.94	GHSR (0.55)	IL23RGHSRCD47
SCHEMBL30092900	0.92	KISS1R (0.54)	IL23RERAP2NPY2RPRMT1
SCHEMBL30130537	0.92	KISS1R (0.54)	IL23RERAP2NPY2RPRMT1
SCHEMBL30130551	0.92	KISS1R (0.54)	IL23RERAP2NPY2RPRMT1
SCHEMBL30130577	0.92	KISS1R (0.54)	IL23RERAP2NPY2RPRMT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-RE34165-E	Pentapeptide immunoregulators	ORTHO PHARMACEUTICAL CORPORATION (US)	1993-01-19	—	—	US	disclosed
US-4629723-A	IMMUNOREGULATING PEPTIDES	ORTHO PHARMACEUTICAL CORPORATION (US)	1986-12-16	—	—	US	disclosed
EP-0166612-A2	Potent thymopentin analogs	ORTHO PHARMACEUTICAL CORPORATION (US)	1986-01-02	—	—	EP	disclosed