Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.50 |
| ▸ | IDO1 | P14902 | 2/20 | 0.50 |
| ▸ | AHR | P35869 | 1/20 | 0.50 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | HK1 | P19367 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | GALK1 | P51570 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.42 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.41 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9056376 | 0.79 | AHR (0.53) | LRRK2AHRPDK2NPC1KMT2A | |
| SCHEMBL9056372 | 0.79 | AHR (0.53) | LRRK2AHRPDK2NPC1KMT2A | |
| SCHEMBL1816980 | 0.72 | AHR (0.63) | LRRK2AHRPDK2NPC1KMT2A | |
| SCHEMBL6249305 | 0.71 | AHR (0.61) | LRRK2AHRPDK2NPC1KMT2A | |
| Oxindole SCHEMBL29260649 | 0.70 | AHR (0.95) | AHRPDK2NPC1KMT2AMAPT | |
| SCHEMBL4356821 | 0.69 | AHR (0.59) | LRRK2AHRPDK2NPC1KMT2A | |
| SCHEMBL2087698 | 0.69 | TDP2 (0.66) | LRRK2AHRPDK2NPC1KMT2A | |
| SCHEMBL2217338 | 0.68 | NPC1 (0.55) | AHRPDK2NPC1KMT2AMAPT | |
| SCHEMBL3456349 | 0.68 | NPC1 (0.55) | AHRPDK2NPC1KMT2AMAPT | |
| Oxindole SCHEMBL19504 | 0.68 | AHR (1.00) | AHRPDK2NPC1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5216227-A | — | — | None | — | — | JP | disclosed |
| JP-H05216227-A | PHOTOPOLYMERIZABLE COMPOSITION | KONICA CORP | 1993-08-27 | — | — | JP | disclosed |