Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 4/20 | 0.59 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.40 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.40 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.40 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.40 |
| ▸ | P2RY2 | P41231 | 6/20 | 0.36 |
| ▸ | P2RY6 | Q15077 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | P2RY4 | P51582 | 2/20 | 0.35 |
| ▸ | TK1 | P04183 | 1/20 | 0.35 |
| ▸ | TYMS | P04818 | 1/20 | 0.35 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2114483 | 0.92 | DUT (0.52) | DUTSLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL6330034 | 0.88 | DUT (0.51) | DUTSLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL6330032 | 0.88 | DUT (0.51) | DUTSLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL6328518 | 0.88 | DUT (0.50) | DUTMEN1KMT2ATK1TYMS | |
| SCHEMBL15094053 | 0.84 | DUT (0.50) | DUTSLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL6034458 | 0.84 | DUT (0.53) | DUTSLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL9723513 | 0.83 | DUT (0.46) | DUTSLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL28515509 | 0.83 | DUT (0.46) | DUTMEN1KMT2ATK1TYMS | |
| SCHEMBL51722 | 0.83 | DUT (0.53) | DUTSLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL4954183 | 0.83 | DUT (0.53) | DUTSLC28A1SLC28A2SLC29A1SLC28A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5190926-A | HIV virus | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 1993-03-02 | — | — | US | disclosed |
| US-5145840-A | Treatment of virac and bacterial infections; aids | BURROUGHS WELLCOME CO. (US) | 1992-09-08 | — | — | US | disclosed |
| US-5064946-A | 3-azido-2,3-dideoxy-B-D-erythro-pentofuranosyl derivatives of 4(1H)-pyrimidinones; antiretroviral, anti-AIDS | BURROUGHS WELLCOME CO. (US) | 1991-11-12 | — | — | US | disclosed |
| EP-0217580-A2 | Therapeutic nucleosides | THE WELLCOME FOUNDATION LIMITED (GB) | 1987-04-08 | — | — | EP | disclosed |