SCHEMBL51722

SCHEMBL51722

O=c1ccn([C@H]2C[C@H](O)[C@@H](C(O)F)O2)c(=O)[nH]1

nearest known ligand 0.53

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
DUT P33316 4/20 0.53
SLC28A1 O00337 1/20 0.42
SLC28A2 O43868 1/20 0.42
SLC29A1 Q99808 1/20 0.42
SLC28A3 Q9HAS3 1/20 0.42
LMNA P02545 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
P2RY2 P41231 5/20 0.38
P2RY6 Q15077 2/20 0.38
ALOX12 P18054 1/20 0.37
ADRA1A P35348 1/20 0.37
TK1 P04183 3/20 0.37
P2RY4 P51582 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4954183 1.00 DUT (0.53) DUTSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL6034458 0.91 DUT (0.53) DUTSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL15771583 0.88 DUT (0.51) DUTSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL414704 0.88 DUT (0.51) DUTSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL249821 0.88 DUT (0.51) DUTSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL10765602 0.88 DUT (0.51) DUTSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL2056622 0.88 DUT (0.51) DUTSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL28745696 0.88 DUT (0.51) DUTSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL3340603 0.87 DUT (0.50) DUTSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL41471 0.87 DUT (0.50) DUTSLC28A1SLC28A2SLC29A1SLC28A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 10880 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12570704-B2 Functionally modified maytansinoids and compositions and methods of use thereof University of Georgie Research Foundation, Inc. (US) 2026-03-10 US claimed
US-20250268993-A1 ALKALINE PHOSPHATE-BASED ONCOLOGY TREATMENTS THERIVA BIOLOGICS, INC. 2025-08-28 US claimed
EP-4605009-A2 GLYCAN CONJUGATE COMPOSITIONS AND METHODS GanNA Bio, Inc. (US) 2025-08-27 EP claimed
EP-4595966-A1 USE OF NPY/Y5R INHIBITOR IN TREATING LIVER METASTASIS Friedrich-Alexander-Universität Erlangen-Nürnberg (DE) 2025-08-06 EP claimed
US-20250242035-A1 GLYCAN CONJUGATE COMPOSITIONS AND METHODS GANNA BIO, INC. 2025-07-31 US claimed
US-12318434-B2 Alkaline phosphate-based oncology treatments THERIVA BIOLOGICS, INC. (US) 2025-06-03 US claimed
EP-4558641-A1 METHODS FOR DETECTION AND REDUCTION OF SAMPLE PREPARATION-INDUCED METHYLATION ARTIFACTS Guardant Health, Inc. (US) 2025-05-28 EP claimed
CN-119923475-A Method for detecting and reducing sample preparation induced methylation artifacts 夸登特健康公司 2025-05-02 CN claimed
CN-119838022-A Amatoxin conjugates containing branched linkers 杭州多禧生物科技有限公司 2025-04-18 CN claimed
US-20250116671-A1 Kinase Activity In Tumors INSTITUTE FOR CANCER RES D/B/A THE RES INSTITUTE OF FOX CHASE CANCER CENTER (US) 2025-04-10 US claimed
WO-1991009130-A1 FERMENTATION PROCESS FOR THE PRODUCTION OF PYRIMIDINE DEOXYRIBONUCLEOSIDES CHEMGEN CORPORATION (US) 1991-06-27 WO claimed
US-5023172-A Forming clonable hybrid multicellular spheroids of feeder cells entrapping tumor cells to provide them with an in vivo environment; evaluation of treatments THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 1991-06-11 US claimed
EP-0352988-A2 Polynucleotide probes for horses HER MAJESTY THE QUEEN IN RIGHT OF NEW ZEALAND (NZ) 1990-01-31 EP claimed
CN-88102026-A CHEMO-RADIO-IMMUNO-CONJUGATES 1988-09-28 CN claimed
EP-0282057-A2 Chemo-radio-immuno-conjugates THE BOARD OF REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 1988-09-14 EP claimed
US-4585736-A Flow cytometric measurement of total DNA and incorporated halodeoxyuridine THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY (US) 1986-04-29 US claimed
US-4416875-A ANTITUMOR AGENTS FUNAI YAKUHIN KOGYO KABUSHIKI KAISHA (JP) 1983-11-22 US claimed
EP-0038357-A4 HYDROLYTIC ENZYME-ACTIVATIBLE PRO-DRUGS. UNIV ILLINOIS (US) 1982-03-22 EP claimed
EP-0038357-A1 HYDROLYTIC ENZYME-ACTIVATIBLE PRO-DRUGS University of Illinois Foundation (US) 1981-10-28 EP claimed
WO-1981001145-A1 HYDROLYTIC ENZYME-ACTIVATIBLE PRO-DRUGS UNIV ILLINOIS (US) 1981-04-30 WO claimed