Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | PPOX | P50336 | 1/20 | 0.39 |
| ▸ | WDR5 | P61964 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | USP10 | Q14694 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
| ▸ | CCR6 | P51684 | 1/20 | 0.32 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.32 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9552008 | 0.81 | TDP1 (0.44) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL9555718 | 0.80 | SMN1; SMN2 (0.42) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL11114839 | 0.78 | TDP1 (0.45) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL7148282 | 0.78 | MEN1 (0.69) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL11266141 | 0.76 | TDP1 (0.45) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL11213666 | 0.76 | TDP1 (0.57) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL9120594 | 0.75 | MEN1 (0.52) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10877259 | 0.74 | ALDH1A1 (0.42) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL11272565 | 0.73 | TDP1 (0.41) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL11190333 | 0.73 | TDP1 (0.43) | TDP1MEN1KMT2ATTRPPOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5189169-A | Postemergence herbicides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-02-23 | — | — | US | disclosed |
| US-5084083-A | Phenylthiazolecarboxylic acid derivative herbicides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-01-28 | — | — | US | disclosed |