Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.37 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.35 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9553677 | 0.91 | FOLH1 (0.42) | FOLH1AGTR1AGTR2PPARGLTB4R | |
| SCHEMBL9553513 | 0.90 | AGTR1 (0.47) | AGTR1AGTR2PPARG | |
| SCHEMBL9552725 | 0.85 | FOLH1 (0.41) | FOLH1AGTR1AGTR2 | |
| SCHEMBL9552491 | 0.85 | AGTR1 (0.47) | AGTR1AGTR2 | |
| SCHEMBL9552687 | 0.83 | FOLH1 (0.44) | FOLH1AGTR1AGTR2PPARGLTB4R | |
| SCHEMBL9552536 | 0.83 | AGTR1 (0.48) | AGTR1AGTR2PPARG | |
| SCHEMBL9553445 | 0.82 | AGTR1 (0.47) | AGTR1AGTR2PPARG | |
| SCHEMBL9749873 | 0.81 | FOLH1 (0.48) | FOLH1AGTR1AGTR2CNR2LTB4R | |
| SCHEMBL9552424 | 0.81 | AGTR1 (0.50) | AGTR1AGTR2PPARG | |
| SCHEMBL9531976 | 0.80 | AGTR1 (0.40) | FOLH1AGTR1AGTR2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5229406-A | Treatment of glaucoma | G. D. SEARLE & CO. (US) | 1993-07-20 | — | — | US | disclosed |