SCHEMBL955236

SCHEMBL955236

CC=CC1=NC(C)(C)C(=O)O1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19790041 0.89
SCHEMBL8627083 0.66
SCHEMBL19790038 0.62
SCHEMBL7752813 0.62 TP53 (0.31)
SCHEMBL6698827 0.62 TP53 (0.31)
SCHEMBL13196247 0.61
SCHEMBL22453298 0.61
SCHEMBL8628125 0.61 TP53 (0.30)
SCHEMBL12756282 0.60
SCHEMBL13957070 0.60

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 279 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7270678-B2 For reducing or eliminating lens epithelial cell growth thereon, reducing or eliminating silicone oil absorption upon subsequent surgical exposure and/ or reducing implantation inserter friction BAUSCH & LOMB INCORPORATED (US) 2007-09-18 US claimed
US-7083646-B2 Surface modification of functional group-containing intraocular lenses BAUSCH & LOMB INCORPORATED (US) 2006-08-01 US claimed
JP-2005531363-A 2005-10-20 JP claimed
EP-1519760-A1 INTRAOCULAR LENSES WITH MODIFIED SURFACE BAUSCH & LOMB INCORPORATED (US) 2005-04-06 EP claimed
EP-1519761-A1 INTRAOCULAR LENSES WITH MODIFIED SURFACE BAUSCH & LOMB INCORPORATED (US) 2005-04-06 EP claimed
US-20040006386-A1 Surface modification of functional group-containing intraocular lenses BAUSCH HEALTH MAGYARORSZAG KFT (A/K/A BAUSCH HEALTH HUNGARY LLC) (HU) 2004-01-08 US claimed
WO-2004002546-A1 INTRAOCULAR LENSES WITH MODIFIED SURFACE BAUSCH & LOMB INCORPORATED (US) 2004-01-08 WO claimed
US-20040006385-A1 Surface modification of functional group-containing intraocular lenses with catalyst containing reactive polymer system BAUSCH HEALTH MAGYARORSZAG KFT (A/K/A BAUSCH HEALTH HUNGARY LLC) (HU) 2004-01-08 US claimed
WO-2004002545-A1 INTRAOCULAR LENSES WITH MODIFIED SURFACE BAUSCH & LOMB INCORPORATED (US) 2004-01-08 WO claimed
JP-3015103-B2 2000-03-06 JP claimed
US-5352714-A Curing and hydrating an unsaturated oxazolone monomer, a polysiloxane having acrylated end groups and an unsaturated monomer; contact lenses BAUSCH & LOMB INCORPORATED (US) 1994-10-04 US claimed
EP-0611379-A1 WETTABLE SILICONE HYDROGEL COMPOSITIONS AND METHODS FOR THEIR MANUFACTURE. BAUSCH & LOMB (US) 1994-08-24 EP claimed
EP-0611380-A1 WETTABLE SILICONE HYDROGEL COMPOSITIONS AND METHODS FOR THEIR MANUFACTURE. BAUSCH & LOMB (US) 1994-08-24 EP claimed
EP-0338656-B1 Polymeric silicone-based materials with high oxygen permeability BAUSCH & LOMB (US) 1994-03-02 EP claimed
US-5274008-A Using a mold surface having improved wettability made of a copolymer of an acrylic mononitrile and a monomer that enhances melt processability; contact lenses BAUSCH & LOMB INCORPORATED (US) 1993-12-28 US claimed
EP-0560916-A1 MOLD MATERIALS FOR SILICONE CONTAINING LENS MATERIALS. BAUSCH & LOMB (US) 1993-09-22 EP claimed
WO-1993009155-A1 WETTABLE SILICONE HYDROGEL COMPOSITIONS AND METHODS FOR THEIR MANUFACTURE BAUSCH & LOMB INCORPORATED (US) 1993-05-13 WO claimed
WO-1993009154-A1 WETTABLE SILICONE HYDROGEL COMPOSITIONS AND METHODS FOR THEIR MANUFACTURE BAUSCH & LOMB INCORPORATED (US) 1993-05-13 WO claimed
WO-1992009421-A2 MOLD MATERIALS FOR SILICONE CONTAINING LENS MATERIALS BAUSCH & LOMB INCORPORATED (US) 1992-06-11 WO claimed
EP-0091956-B1 ACRYLAMIDOACYLATED OLIGOMERS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1986-02-26 EP claimed