SCHEMBL95542

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL95161	0.88	TP53 (0.64)	SMN1; SMN2TP53RAB9AKLF5NPC1
	SCHEMBL95543	0.85	SMN1; SMN2 (0.69)	SMN1; SMN2TP53RAB9AKLF5NPC1
	SCHEMBL157198	0.83	RAB9A (0.62)	SMN1; SMN2TP53RAB9AKLF5NPC1
	SCHEMBL2245578	0.81	TP53 (0.60)	SMN1; SMN2TP53RAB9AKLF5NPC1
	SCHEMBL95162	0.81	RAB9A (0.64)	SMN1; SMN2TP53RAB9AKLF5NPC1
	SCHEMBL417374	0.74	NPC1 (0.61)	SMN1; SMN2TP53RAB9AKLF5NPC1
	SCHEMBL876239	0.73	S1PR1 (0.78)	—
	SCHEMBL4227167	0.72	RAB9A (0.53)	SMN1; SMN2TP53RAB9AKLF5NPC1
	SCHEMBL8830004	0.72	NPC1 (0.59)	SMN1; SMN2TP53RAB9AKLF5NPC1
	SCHEMBL2088387	0.72	S1PR1 (0.65)	LMNAMAPTSIRT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.