Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 19/20 | 0.41 |
| ▸ | CTSD | P07339 | 1/20 | 0.37 |
| ▸ | PGA5 | P0DJD9 | 1/20 | 0.37 |
| ▸ | CTSE | P14091 | 1/20 | 0.37 |
| ▸ | PGC | P20142 | 1/20 | 0.37 |
| ▸ | CCR1 | P32246 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9555200 | 1.00 | REN (0.41) | RENCTSDPGA5CTSEPGC | |
| SCHEMBL9554322 | 1.00 | REN (0.41) | RENCTSDPGA5CTSEPGC | |
| SCHEMBL7329529 | 0.89 | REN (0.50) | RENCTSDPGA5CTSEPGC | |
| SCHEMBL7277640 | 0.88 | REN (0.38) | RENCTSDPGA5CTSE | |
| SCHEMBL9554906 | 0.88 | REN (0.39) | RENCTSDPGA5CTSEPGC | |
| SCHEMBL9554583 | 0.87 | REN (0.44) | RENCTSDPGA5CTSEPGC | |
| SCHEMBL9554471 | 0.87 | REN (0.44) | RENCTSDPGA5CTSEPGC | |
| SCHEMBL9554500 | 0.87 | REN (0.44) | RENCTSDPGA5CTSEPGC | |
| SCHEMBL9554748 | 0.87 | REN (0.44) | RENCTSD | |
| SCHEMBL9554834 | 0.86 | REN (0.32) | RENCTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5250517-A | Hypotensive and cardiotonic agents; cardiac insufficiency | HOFFMANN-LA ROCHE INC. (US) | 1993-10-05 | — | — | US | disclosed |