Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 20/20 | 0.38 |
| ▸ | CTSD | P07339 | 4/20 | 0.37 |
| ▸ | CTSE | P14091 | 4/20 | 0.37 |
| ▸ | PGA5 | P0DJD9 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9554322 | 0.88 | REN (0.41) | RENCTSDCTSEPGA5 | |
| SCHEMBL9555200 | 0.88 | REN (0.41) | RENCTSDCTSEPGA5 | |
| SCHEMBL9554457 | 0.88 | REN (0.41) | RENCTSDCTSEPGA5 | |
| SCHEMBL7276395 | 0.88 | REN (0.43) | RENCTSDCTSEPGA5 | |
| SCHEMBL10510052 | 0.86 | REN (0.42) | RENCTSDCTSE | |
| SCHEMBL9554910 | 0.86 | REN (0.42) | RENCTSDCTSE | |
| SCHEMBL7329529 | 0.86 | REN (0.50) | RENCTSDCTSEPGA5 | |
| SCHEMBL7279038 | 0.85 | REN (0.35) | RENCTSDCTSEPGA5 | |
| SCHEMBL9225629 | 0.82 | REN (0.40) | REN | |
| SCHEMBL7266011 | 0.82 | PSEN1 (0.49) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0391180-A2 | Peptide derivatives of amino acids having a renin-inhibiting effect | F. HOFFMANN-LA ROCHE AG (CH) | 1990-10-10 | — | — | EP | disclosed |