Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PREP | P48147 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5171011 | 0.90 | HSD17B10 (0.49) | CTSKHSD17B10HPGDSMN1; SMN2MEN1 | |
| SCHEMBL2355780 | 0.90 | HSD17B10 (0.49) | CTSKHSD17B10HPGDSMN1; SMN2MEN1 | |
| SCHEMBL7855614 | 0.90 | HSD17B10 (0.49) | CTSKHSD17B10HPGDSMN1; SMN2MEN1 | |
| SCHEMBL9555116 | 0.88 | HPGD (0.48) | CTSKHSD17B10HPGDSMN1; SMN2RECQL | |
| SCHEMBL7380781 | 0.88 | HPGD (0.48) | CTSKHSD17B10HPGDSMN1; SMN2RECQL | |
| SCHEMBL5275535 | 0.84 | HSD17B10 (0.47) | CTSKHSD17B10CHRM2CHRM1CHRM3 | |
| SCHEMBL6166916 | 0.84 | CTSK (0.49) | CTSKHSD17B10CHRM2CHRM1CHRM3 | |
| SCHEMBL4919669 | 0.84 | HSD17B10 (0.47) | CTSKHSD17B10CHRM2CHRM1CHRM3 | |
| SCHEMBL16067363 | 0.84 | CTSK (0.49) | CTSKHSD17B10CHRM2CHRM1CHRM3 | |
| SCHEMBL25177092 | 0.80 | HSD17B10 (0.41) | CTSKHSD17B10CHRM2CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5250517-A | Hypotensive and cardiotonic agents; cardiac insufficiency | HOFFMANN-LA ROCHE INC. (US) | 1993-10-05 | — | — | US | claimed |