Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.74 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.74 |
| ▸ | TSHR | P16473 | 3/20 | 0.71 |
| ▸ | MEN1 | O00255 | 2/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | ANPEP | P15144 | 3/20 | 0.60 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12252067 | 0.86 | MAPT (0.69) | MAPTL3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL11657783 | 0.85 | L3MBTL1 (1.00) | MAPTL3MBTL1TSHRMEN1KMT2A | |
| SCHEMBL7206283 | 0.83 | MAPK1 (0.76) | MAPTL3MBTL1TSHRMEN1KMT2A | |
| SCHEMBL6445570 | 0.83 | MAPK1 (0.76) | MAPTL3MBTL1TSHRMEN1KMT2A | |
| SCHEMBL5175905 | 0.83 | MAPK1 (0.76) | MAPTL3MBTL1TSHRMEN1KMT2A | |
| SCHEMBL24568368 | 0.83 | MAPT (0.65) | MAPTL3MBTL1TSHRMEN1KMT2A | |
| SCHEMBL10883477 | 0.83 | MAPT (0.65) | MAPTL3MBTL1TSHRMEN1KMT2A | |
| SCHEMBL8018817 | 0.82 | MAPK1 (0.61) | MAPTL3MBTL1TSHRALDH1A1ANPEP | |
| SCHEMBL5611837 | 0.81 | MAPT (0.63) | MAPTL3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL6436940 | 0.81 | EPHX2 (0.68) | MAPTL3MBTL1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5250517-A | Hypotensive and cardiotonic agents; cardiac insufficiency | HOFFMANN-LA ROCHE INC. (US) | 1993-10-05 | — | — | US | disclosed |