Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | ANPEP | P15144 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | MME | P08473 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6445570 | 0.89 | MAPK1 (0.76) | MAPK1TSHRANPEPMAPTL3MBTL1 | |
| SCHEMBL5175905 | 0.89 | MAPK1 (0.76) | MAPK1TSHRANPEPMAPTL3MBTL1 | |
| SCHEMBL7206283 | 0.89 | MAPK1 (0.76) | MAPK1TSHRANPEPMAPTL3MBTL1 | |
| SCHEMBL9554654 | 0.82 | MAPT (0.74) | MAPK1TSHRANPEPMAPTL3MBTL1 | |
| SCHEMBL12252067 | 0.82 | MAPT (0.69) | ANPEPMAPTL3MBTL1ALDH1A1ATM | |
| SCHEMBL7599136 | 0.80 | ALDH1A1 (0.53) | MAPTL3MBTL1ALDH1A1MME | |
| SCHEMBL7876545 | 0.80 | ALDH1A1 (0.53) | MAPTL3MBTL1ALDH1A1MME | |
| SCHEMBL31336702 | 0.80 | ALDH1A1 (0.53) | MAPTL3MBTL1ALDH1A1MME | |
| SCHEMBL7293707 | 0.80 | ALDH1A1 (0.53) | MAPTL3MBTL1ALDH1A1MME | |
| SCHEMBL2074599 | 0.80 | ALDH1A1 (0.53) | MAPTL3MBTL1ALDH1A1MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0728144-B1 | PEPTIDYL COMPOUNDS AND THEIR THERAPEUTIC USE AS INHIBITORS OF METALLOPROTEINASES | DARWIN DISCOVERY LTD (GB) | 2000-01-19 | — | — | EP | disclosed |
| US-5853623-A | Peptidyl compounds and their therapeutic use as inhibitors of metalloproteinases | CHIROSCIENCE LIMITED (GB) | 1998-12-29 | — | — | US | disclosed |
| EP-0728144-A1 | PEPTIDYL COMPOUNDS AND THEIR THERAPEUTIC USE AS INHIBITORS OF METALLOPROTEINASES | Chiroscience Limited (GB) | 1996-08-28 | — | — | EP | disclosed |
| WO-1995013289-A1 | PEPTIDYL COMPOUNDS AND THEIR THERAPEUTIC USE AS INHIBITORS OF METALLOPROTEINASES | CHIROSCIENCE LIMITED (GB) | 1995-05-18 | — | — | WO | disclosed |