Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 2/20 | 0.47 |
| ▸ | PTPRA | P18433 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.42 |
| ▸ | FDPS | P14324 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | FPR2 | P25090 | 1/20 | 0.37 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.37 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.37 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.37 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KDM6B | O15054 | 1/20 | 0.36 |
| ▸ | TERT | O14746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL334040 | 1.00 | TBXAS1 (0.47) | TBXAS1PTPRATAAR1FDPSSMN1; SMN2 | |
| SCHEMBL11456188 | 0.83 | TBXAS1 (0.49) | TBXAS1TAAR1FDPSSMN1; SMN2GAA | |
| Histidine SCHEMBL27753697 | 0.80 | GRIA1 (0.39) | TBXAS1PTPRASMN1; SMN2ALOX15GRIA1 | |
| SCHEMBL5185101 | 0.80 | TBXAS1 (0.46) | TBXAS1TAAR1FDPSSMN1; SMN2GAA | |
| SCHEMBL7511041 | 0.80 | TBXAS1 (0.46) | TBXAS1TAAR1FDPSSMN1; SMN2GAA | |
| SCHEMBL24834446 | 0.80 | GRIA2 (0.51) | TBXAS1TAAR1FDPSALOX15FPR2 | |
| SCHEMBL3838965 | 0.80 | GRIA2 (0.51) | TBXAS1TAAR1FDPSALOX15FPR2 | |
| SCHEMBL781663 | 0.80 | GRIA2 (0.51) | TBXAS1TAAR1FDPSALOX15FPR2 | |
| SCHEMBL31544487 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL11090438 | 0.77 | GRIA1 (0.49) | TBXAS1TAAR1FDPSALOX15FPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5250517-A | Hypotensive and cardiotonic agents; cardiac insufficiency | HOFFMANN-LA ROCHE INC. (US) | 1993-10-05 | — | — | US | disclosed |
| EP-0310918-A2 | Peptide-like amino-acid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1989-04-12 | — | — | EP | disclosed |