SCHEMBL781663

SCHEMBL781663

N[C@@H](Cc1ncc[nH]1)C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIA2 P42262 2/20 0.51
GRIA1 P42261 1/20 0.51
GRIA3 P42263 1/20 0.51
GRIA4 P48058 1/20 0.51
SLC7A5 Q01650 3/20 0.47
CYP3A4 P08684 2/20 0.47
TBXAS1 P24557 2/20 0.46
HSD17B10 Q99714 2/20 0.44
PKM P14618 2/20 0.43
ALPI P09923 1/20 0.43
PTGS1 P23219 1/20 0.43
XIAP P98170 1/20 0.43
CYP1A2 P05177 1/20 0.42
TAAR1 Q96RJ0 1/20 0.41
FDPS P14324 1/20 0.40
KDM4E B2RXH2 2/20 0.40
MEN1 O00255 2/20 0.40
LMNA P02545 2/20 0.40
MAPT P10636 2/20 0.40
BLM P54132 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3838965 1.00 GRIA2 (0.51) GRIA2GRIA1GRIA3GRIA4SLC7A5
SCHEMBL24834446 1.00 GRIA2 (0.51) GRIA2GRIA1GRIA3GRIA4SLC7A5
Hydrochloric Acid SCHEMBL11090438 0.97 GRIA1 (0.49) GRIA2GRIA1GRIA3GRIA4SLC7A5
Imidazole SCHEMBL8049134 0.88 GRIA1 (0.46) GRIA2GRIA1GRIA3GRIA4SLC7A5
Histidine SCHEMBL1536141 0.86 GRIA1 (0.42) GRIA2GRIA1GRIA3GRIA4SLC7A5
SCHEMBL10838551 0.86 TBXAS1 (0.42) GRIA2GRIA1GRIA3GRIA4TBXAS1
Hydrochloric Acid SCHEMBL10837657 0.84 TBXAS1 (0.44) GRIA2GRIA1GRIA3GRIA4TBXAS1
SCHEMBL3337299 0.84 FDPS (0.42) GRIA2GRIA1GRIA3GRIA4TBXAS1
SCHEMBL1176949 0.83 TBXAS1 (0.51) GRIA2GRIA1GRIA3GRIA4SLC7A5
SCHEMBL11456188 0.81 TBXAS1 (0.49) GRIA2GRIA1GRIA3GRIA4TBXAS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 244 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240400499-A1 NOVEL AMINO ACID DERIVATIVES PEPTIDREAM INC (JP) 2024-12-05 US claimed
EP-2124880-B1 FLUORESCENT NANOPARTICLES EXCHANGE IMAGING TECH GMBH (DE) 2018-03-21 EP claimed
EP-1787659-B1 Fluorescent nanoparticles EXCHANGE IMAGING TECH GMBH (DE) 2017-03-22 EP claimed
US-8974767-B2 Fluorescent nanoparticles SIGNALOMICS GMBH (AT) 2015-03-10 US claimed
EP-2292837-B1 Triazinylaminostilbene disulphonic acid mixtures CLARIANT INT LTD (CH) 2014-06-04 EP claimed
EP-2159044-B1 Nanocrystals LIFE TECHNOLOGIES CORP (US) 2012-05-16 EP claimed
EP-1520073-B1 TRIAZINNYLAMINOSTILBENE DISULPHONIC ACID MIXTURES BASF SE (DE) 2012-01-18 EP claimed
EP-2159044-A1 Nanocrystals Life Technologies Corporation (US) 2010-03-03 EP claimed
EP-1456022-B1 NANOCRYSTALS LIFE TECHNOLOGIES CORP (US) 2009-11-11 EP claimed
US-20090226371-A1 FLUORESCENT NANOPARTICLES SIGNALOMICS GMBH (AT) 2009-09-10 US claimed
US-20020017001-A1 Flourescent whitening agents ROHRINGER PETER (CH) 2002-02-14 US claimed
EP-1166179-A1 PROCESS FOR REMOVING STAIN IN A PHOTOGRAPHIC MATERIAL Ciba SC Holding AG (CH) 2002-01-02 EP claimed
US-20010014989-A1 Fluorescent whitening agents ROHRINGER PETER (CH) 2001-08-23 US claimed
EP-1123929-A1 Fluorescent whitening agents Ciba SC Holding AG (CH) 2001-08-16 EP claimed
US-6143889-A Asymmetric stilbene compounds CIBA SPECIALTY CHEMICALS CORPORATION (US) 2000-11-07 US claimed
US-6143888-A TREATING THE SUBSTRATE WITH A TRIAZINE BASED ULTRAVIOLET ABSORPTION COMPOUND TO INHIBIT THE EFFECT OF AN ANIONIC FLUORECENT WHITENING AGENT CIBA SPECIALTY CHEMICALS CORPORATION (US) 2000-11-07 US claimed
WO-2000055688-A1 PROCESS FOR REMOVING STAIN IN A PHOTOGRAPHIC MATERIAL CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2000-09-21 WO claimed
US-6084065-A FOR AGRICULTURAL USE ISAGRO SPA (IT) 2000-07-04 US claimed
EP-0922699-A1 Asymmetric stilbene compounds useful as sun protection agents Ciba SC Holding AG (CH) 1999-06-16 EP claimed
EP-0652229-A2 Oligopeptides with fungicidal activity ISAGRO S.p.A. (IT) 1995-05-10 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240400499-A1 NOVEL AMINO ACID DERIVATIVES BCAT1, BCAT2, PELP1 GRIA2 1319/4885GRIA1 1487/4885GRIA3 1691/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.