Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | AKT1 | P31749 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7440502 | 0.88 | SMN1; SMN2 (0.45) | SMN1; SMN2HIF1ASLC6A2TAAR1BLM | |
| SCHEMBL8287363 | 0.87 | SMN1; SMN2 (0.50) | SMN1; SMN2HIF1ASLC6A2TAAR1BLM | |
| SCHEMBL7001330 | 0.80 | MAPT (0.42) | SMN1; SMN2HIF1ASLC6A2TAAR1RECQL | |
| SCHEMBL1632109 | 0.79 | SLC6A2 (0.52) | SMN1; SMN2HIF1ASLC6A2TAAR1BLM | |
| SCHEMBL5180745 | 0.79 | SLC6A2 (0.52) | SMN1; SMN2HIF1ASLC6A2TAAR1BLM | |
| SCHEMBL8745476 | 0.79 | SLC6A2 (0.52) | SMN1; SMN2HIF1ASLC6A2TAAR1BLM | |
| Hydrochloric Acid SCHEMBL1311456 | 0.78 | SMN1; SMN2 (0.50) | SMN1; SMN2HIF1ASLC6A2TAAR1BLM | |
| Hydrochloric Acid SCHEMBL2210722 | 0.78 | SMN1; SMN2 (0.50) | SMN1; SMN2HIF1ASLC6A2TAAR1BLM | |
| Hydrochloric Acid SCHEMBL2210717 | 0.78 | SMN1; SMN2 (0.50) | SMN1; SMN2HIF1ASLC6A2TAAR1BLM | |
| Methyl Alcohol SCHEMBL11329639 | 0.76 | SMN1; SMN2 (0.49) | SMN1; SMN2HIF1ASLC6A2TAAR1BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5250517-A | Hypotensive and cardiotonic agents; cardiac insufficiency | HOFFMANN-LA ROCHE INC. (US) | 1993-10-05 | — | — | US | disclosed |
| EP-0310918-A2 | Peptide-like amino-acid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1989-04-12 | — | — | EP | disclosed |