Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ANPEP | P15144 | 1/20 | 0.34 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9555706 | 0.91 | CA1 (0.46) | TDP1CA1CA2CA9L3MBTL1 | |
| SCHEMBL9555702 | 0.90 | L3MBTL1 (0.43) | TDP1CA1CA2CA9L3MBTL1 | |
| SCHEMBL7384000 | 0.84 | TSHR (0.52) | TDP1CA1CA2CA9L3MBTL1 | |
| SCHEMBL9555700 | 0.83 | TDP1 (0.42) | TDP1CA1CA2CA9L3MBTL1 | |
| SCHEMBL7265454 | 0.83 | NPSR1 (0.43) | TDP1CA1CA2CA9L3MBTL1 | |
| SCHEMBL7377074 | 0.80 | L3MBTL1 (0.56) | L3MBTL1PKMTSHRIDO1NPC1 | |
| SCHEMBL28209116 | 0.80 | CA1 (0.46) | TDP1CA1CA2CA9L3MBTL1 | |
| SCHEMBL9179785 | 0.77 | ALDH1A1 (0.33) | TDP1ALDH1A1 | |
| SCHEMBL2817045 | 0.75 | CA1 (0.48) | TDP1CA1CA2CA9L3MBTL1 | |
| SCHEMBL7271516 | 0.75 | HTR2A (0.49) | L3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5189023-A | Hypotensive agent | AMERICAN CYANAMID COMPANY (US) | 1993-02-23 | — | — | US | disclosed |