Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.55 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.50 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | AHCY | P23526 | 4/20 | 0.42 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.40 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9417190 | 1.00 | CYP3A4 (0.55) | CYP3A4FGFR1SLC22A6ADORA2AADORA1 | |
| SCHEMBL9555564 | 1.00 | CYP3A4 (0.55) | CYP3A4FGFR1SLC22A6ADORA2AADORA1 | |
| SCHEMBL9417218 | 0.88 | CYP3A4 (0.49) | CYP3A4FGFR1CYP2D6 | |
| SCHEMBL9555568 | 0.86 | FAP (0.44) | CYP3A4FGFR1SLC22A6ADORA2AADORA1 | |
| SCHEMBL9555527 | 0.86 | FAP (0.44) | CYP3A4FGFR1SLC22A6ADORA2AADORA1 | |
| SCHEMBL9417158 | 0.86 | FAP (0.44) | CYP3A4FGFR1SLC22A6ADORA2AADORA1 | |
| SCHEMBL9180474 | 0.86 | CYP3A4 (0.57) | CYP3A4FGFR1SLC22A6ADORA2AADORA1 | |
| SCHEMBL9417147 | 0.86 | CYP3A4 (0.42) | CYP3A4FGFR1SLC22A6AHCY | |
| Ammonia Solution, Strong SCHEMBL9128742 | 0.85 | CYP3A4 (0.56) | CYP3A4FGFR1SLC22A6ADORA2AADORA1 | |
| Ammonia Solution, Strong SCHEMBL9128718 | 0.85 | CYP3A4 (0.56) | CYP3A4FGFR1SLC22A6ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5247085-A | Phosphonate containing purine compounds | BEECHAM GROUP P.L.C. (GB) | 1993-09-21 | — | — | US | claimed |
| EP-0405748-A1 | Phosphonoderivative of purine with antiviral activity | Beecham Group p.l.c. (GB) | 1991-01-02 | — | — | EP | claimed |
| US-5247085-A | Phosphonate containing purine compounds | BEECHAM GROUP P.L.C. (GB) | 1993-09-21 | — | — | US | disclosed |
| EP-0405748-A1 | Phosphonoderivative of purine with antiviral activity | Beecham Group p.l.c. (GB) | 1991-01-02 | — | — | EP | disclosed |