Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRB | P23467 | 10/20 | 0.55 |
| ▸ | PTPN2 | P17706 | 3/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.55 |
| ▸ | PTPRA | P18433 | 1/20 | 0.55 |
| ▸ | MMP1 | P03956 | 5/20 | 0.50 |
| ▸ | MMP13 | P45452 | 5/20 | 0.50 |
| ▸ | MMP9 | P14780 | 4/20 | 0.50 |
| ▸ | ACP1 | P24666 | 2/20 | 0.46 |
| ▸ | PTPRC | P08575 | 1/20 | 0.46 |
| ▸ | PTPRG | P23470 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28294369 | 0.78 | MMP8 (0.50) | PTPRBPTPN2PTPN1PTPRAMMP1 | |
| SCHEMBL14518077 | 0.76 | PTPN1 (0.51) | PTPRBPTPN2PTPN1PTPRAMMP1 | |
| SCHEMBL293540 | 0.76 | MMP8 (0.51) | PTPRBPTPN2PTPN1PTPRAMMP8 | |
| SCHEMBL21811199 | 0.76 | MMP8 (0.51) | PTPRBPTPN2PTPN1PTPRAMMP1 | |
| SCHEMBL29277132 | 0.76 | PTPN1 (0.51) | PTPRBPTPN2PTPN1PTPRAMMP1 | |
| SCHEMBL4008616 | 0.75 | MMP8 (0.50) | PTPRBPTPN2PTPN1PTPRAMMP1 | |
| SCHEMBL28040972 | 0.75 | PTPN1 (0.50) | PTPRBPTPN2PTPN1PTPRAMMP1 | |
| Ammonia Solution, Strong SCHEMBL9134412 | 0.75 | PTPRB (0.50) | PTPRBPTPN2PTPN1PTPRAACP1 | |
| SCHEMBL11175367 | 0.74 | PTPRB (0.69) | PTPRBPTPN2PTPN1PTPRAACP1 | |
| SCHEMBL3272206 | 0.73 | MMP8 (0.49) | PTPRBPTPN2PTPN1PTPRAMMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5258362-A | Enzyme inhibitors, amides with oxetane ring | ABBOTT LABORATORIES (US) | 1993-11-02 | — | — | US | disclosed |