Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 4/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16892197 | 0.76 | ALDH1A1 (0.44) | TDP1KMT2AL3MBTL1GSK3BALDH1A1 | |
| SCHEMBL1145696 | 0.76 | ABCG2 (0.44) | TDP1KMT2AL3MBTL1GSK3BABCG2 | |
| SCHEMBL28264412 | 0.76 | ABCG2 (0.44) | TDP1KMT2AL3MBTL1GSK3BABCG2 | |
| SCHEMBL1145699 | 0.76 | ALDH1A1 (0.47) | ABCG2ALDH1A1HPGDLMNASMN1; SMN2 | |
| SCHEMBL8951994 | 0.75 | KDM4C (0.41) | GSK3BABCG2ALDH1A1HPGDLMNA | |
| SCHEMBL161792 | 0.75 | GSK3B (0.54) | TDP1KMT2AL3MBTL1GSK3BABCG2 | |
| SCHEMBL29706697 | 0.75 | GSK3B (0.54) | TDP1KMT2AL3MBTL1GSK3BABCG2 | |
| SCHEMBL11776414 | 0.74 | MGAM (0.42) | KMT2AGSK3BABCG2ALDH1A1HPGD | |
| SCHEMBL14754177 | 0.74 | KDM4E (0.47) | TDP1ALDH1A1HSD17B10HPGDTSHR | |
| SCHEMBL23963395 | 0.73 | TYMS (0.44) | TDP1KMT2AL3MBTL1GSK3BABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104356006-B | Benzylamine, their preparation method and they as anti-inflammatory agent purposes | 拜耳知识产权有限责任公司 | 2017-09-29 | — | — | CN | disclosed |
| US-20110009429-A1 | HETEROCYCLIC COMPOUNDS AS INHIBITORS OF CXCR2 | NOVARTIS AG (CH) | 2011-01-13 | — | — | US | disclosed |
| EP-2257552-A1 | HETEROCYCLIC COMPOUNDS AS INHIBITORS OF CXCR2 | Novartis AG (CH) | 2010-12-08 | — | — | EP | disclosed |
| WO-2009106539-A1 | HETEROCYCLIC COMPOUNDS AS INHIBITORS OF CXCR2 | NOVARTIS AG (CH) | 2009-09-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110009429-A1 | HETEROCYCLIC COMPOUNDS AS INHIBITORS OF CXCR2 | CXCR2, CXCR1, CXCR3 | TDP1 4034/4885KMT2A 2456/4885L3MBTL1 2125/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.