Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 4/20 | 0.57 |
| ▸ | TACR1 | P25103 | 2/20 | 0.55 |
| ▸ | CTSL | P07711 | 3/20 | 0.54 |
| ▸ | CTSS | P25774 | 3/20 | 0.54 |
| ▸ | CTSK | P43235 | 2/20 | 0.54 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9556978 | 1.00 | CTSB (0.57) | CTSBTACR1CTSLCTSSCTSK | |
| SCHEMBL16322884 | 0.95 | CAPN1 (0.58) | CTSBTACR1CTSLCTSSCTSK | |
| SCHEMBL9556498 | 0.95 | CAPN1 (0.58) | CTSBTACR1CTSLCTSSCTSK | |
| SCHEMBL16321202 | 0.95 | CAPN1 (0.58) | CTSBTACR1CTSLCTSSCTSK | |
| SCHEMBL16322231 | 0.95 | CAPN1 (0.58) | CTSBTACR1CTSLCTSSCTSK | |
| SCHEMBL1038643 | 0.95 | CAPN1 (0.58) | CTSBTACR1CTSLCTSSCTSK | |
| SCHEMBL1037693 | 0.88 | CTSL (0.57) | CTSBTACR1CTSLCTSSCTSK | |
| SCHEMBL16323443 | 0.88 | CTSL (0.57) | CTSBTACR1CTSLCTSSCTSK | |
| SCHEMBL16323306 | 0.88 | CTSL (0.57) | CTSBTACR1CTSLCTSSCTSK | |
| SCHEMBL16322478 | 0.88 | CTSL (0.57) | CTSBTACR1CTSLCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5223486-A | Modified oligopeptide containing a diazomethyl ketone group or methylsulfonium group | UNIVERSITY RESEARCH CORPORATION (US) | 1993-06-29 | — | — | US | disclosed |