⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4756560 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL6609957 | 0.97 | — | — | |
| SCHEMBL8279455 | 0.92 | — | — | |
| SCHEMBL4754736 | 0.92 | — | — | |
| SCHEMBL13745011 | 0.90 | DRD2 (0.37) | — | |
| SCHEMBL3372270 | 0.89 | ADH1A (0.50) | — | |
| Hydrochloric Acid SCHEMBL5379324 | 0.89 | ADH1A (0.45) | — | |
| SCHEMBL10102970 | 0.88 | DRD2 (0.36) | — | |
| SCHEMBL3273602 | 0.88 | DRD2 (0.36) | — | |
| SCHEMBL17046171 | 0.87 | ADH1A (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 239 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102186803-A | Salicylic acid derivatives being farnesyl pyrophosphate synthase activity inhibitors | NOVARTIS AG | 2011-09-14 | — | — | CN | claimed |
| WO-2005012297-A9 | BENZIMIDAZOLE, BENZTHIAZOLE AND BENZOXAZOLE DERIVATIVES AND THEIR USE AS LTA4H MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2007-01-04 | — | — | WO | claimed |
| EP-1737823-A2 | NOVEL ALKYNE COMPOUNDS WITH AN MCH-ANTAGONISTIC ACTION AND MEDICAMENTS COMPRISING SAID COMPOUNDS | Boehringer Ingelheim International GmbH (DE) | 2007-01-03 | — | — | EP | claimed |
| EP-1660492-A1 | BENZIMIDAZOLE, BENZTHIAZOLE AND BENZOXAZOLE DERIVATIVES AND THEIR USE AS LTA4H MODULATORS | Janssen Pharmaceutica N.V. (BE) | 2006-05-31 | — | — | EP | claimed |
| WO-2005103002-A2 | NOVEL ALKYNE COMPOUNDS WITH AN MCH-ANTAGONISTIC ACTION AND MEDICAMENTS COMPRISING SAID COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-11-03 | — | — | WO | claimed |
| WO-2005012297-A1 | BENZIMIDAZOLE, BENZTHIAZOLE AND BENZOXAZOLE DERIVATIVES AND THEIR USE AS LTA4H MODULATORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2005-02-10 | — | — | WO | claimed |
| EP-0870756-B1 | Process for the preparation of 3,4-disubstituted dinitroanilines | CFPI NUFARM (FR) | 2001-11-07 | — | — | EP | claimed |
| US-6028226-A | Process for 3,4-disubstituted dinitroanilines | CFPI AGRO (FR) | 2000-02-22 | — | — | US | claimed |
| US-5981800-A | Preparation process for 4-substituted dinitroanilines | CFPI AGRO (FR) | 1999-11-09 | — | — | US | claimed |
| EP-0870756-A1 | Process for the preparation of 3,4-disubstituted dinitroanilines | CFPI AGRO (FR) | 1998-10-14 | — | — | EP | claimed |
| EP-0870755-A1 | Process for the preparation of 4-substituted nitroanilines | CFPI AGRO (FR) | 1998-10-14 | — | — | EP | claimed |
| US-4275238-A | CYCLIZING BUTANEDIOL USING A COBALT CATALYST, ALKYLATING WITH PROPYLAMINE | CIBA-GEIGY CORPORATION (US) | 1981-06-23 | — | — | US | claimed |
| US-4264527-A | REACTING CYCLOPROPYLMETHYLAMINE WITH PROPIONITRILE IN THE PRESENCE OF A HYDROGENATION CATALYST AND HYDROGEN | CIBA-GEIGY CORPORATION (US) | 1981-04-28 | — | — | US | claimed |
| WO-2024015055-A1 | PYRAZOLO[3,4-D]PYRIMIDIN-6-YL-SULFONAMIDE DERIVATIVES FOR THE INHIBITION OF SGK-1 AND TREATMENT OF CANCER | THRYV THERAPEUTICS INC. (CA) | 2024-01-18 | — | — | WO | disclosed |
| US-11426399-B2 | Treatment of aging-associated disease with modulators of leukotriene A4 hydrolase | ALKAHEST, INC. (US) | 2022-08-30 | — | — | US | disclosed |
| US-20220226304-A1 | Treatment of Aging-Associated Disease with Modulators of Leukotriene A4 Hydrolase | ALKAHEST, INC. | 2022-07-21 | — | — | US | disclosed |
| US-4264527-A | REACTING CYCLOPROPYLMETHYLAMINE WITH PROPIONITRILE IN THE PRESENCE OF A HYDROGENATION CATALYST AND HYDROGEN | CIBA-GEIGY CORPORATION (US) | 1981-04-28 | — | — | US | disclosed |
| US-4264527-A | REACTING CYCLOPROPYLMETHYLAMINE WITH PROPIONITRILE IN THE PRESENCE OF A HYDROGENATION CATALYST AND HYDROGEN | CIBA-GEIGY CORPORATION (US) | 1981-04-28 | — | — | US | disclosed |
| US-4264527-A | REACTING CYCLOPROPYLMETHYLAMINE WITH PROPIONITRILE IN THE PRESENCE OF A HYDROGENATION CATALYST AND HYDROGEN | CIBA-GEIGY CORPORATION (US) | 1981-04-28 | — | — | US | disclosed |
| US-4205009-A | USING ANIONIC SURFACTANT | VELSICOL CHEMICAL CORPORATION (US) | 1980-05-27 | — | — | US | disclosed |