Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | ESR1 | P03372 | 1/20 | 0.51 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.51 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | GGT1 | P19440 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | ELANE | P08246 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9557959 | 0.86 | NPC1 (0.48) | KDM4EALDH1A1ELANELMNAMAPT | |
| SCHEMBL9557199 | 0.84 | KDM4E (0.48) | KDM4EHSD17B10HPGDPTGS2ALDH1A1 | |
| SCHEMBL8174989 | 0.80 | POLB (0.50) | KDM4EHSD17B10HPGDALDH1A1TSHR | |
| SCHEMBL9557765 | 0.79 | KMT2A (0.48) | TSHRMAPK1POLBKMT2A | |
| SCHEMBL9557539 | 0.78 | POLB (0.53) | CYP2C9POLB | |
| SCHEMBL9557956 | 0.78 | MEN1 (0.49) | HSD17B10ALDH1A1POLBMEN1KMT2A | |
| SCHEMBL9557914 | 0.78 | HPGD (0.49) | HPGDALDH1A1POLBMEN1KMT2A | |
| SCHEMBL9557258 | 0.77 | CTSD (0.49) | MAPT | |
| SCHEMBL9557412 | 0.76 | SMN1; SMN2 (0.42) | KDM4EHPGDALDH1A1TDP1POLB | |
| SCHEMBL9557599 | 0.76 | SMN1; SMN2 (0.44) | LMNASLC6A3POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5225443-A | Lepidotera and Coleoptera insecticides to protect plants | ROHM AND HAAS COMPANY (US) | 1993-07-06 | — | — | US | disclosed |
| EP-0245950-A2 | Insecticidal n-substituted-n' - substituted-n, n'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1987-11-19 | — | — | EP | disclosed |