Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 1/20 | 0.49 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.45 |
| ▸ | PDE2A | O00408 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | CDK4 | P11802 | 1/20 | 0.41 |
| ▸ | CCND1 | P24385 | 1/20 | 0.41 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.41 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9557959 | 0.91 | NPC1 (0.48) | CTSDABCG2PDE2AMAPTNPSR1 | |
| SCHEMBL20812227 | 0.82 | CTSD (0.49) | CTSDABCG2PDE2AMAPTNPSR1 | |
| SCHEMBL9558221 | 0.81 | CTSD (0.45) | CTSDABCG2PDE2AMAPTNPSR1 | |
| SCHEMBL9557556 | 0.79 | KMT2A (0.49) | HTT | |
| SCHEMBL2541558 | 0.78 | CTSD (0.55) | CTSDABCG2PDE2AMAPTNPC1 | |
| SCHEMBL9557317 | 0.78 | POLB (0.54) | HTT | |
| SCHEMBL9557680 | 0.78 | MEN1 (0.50) | MAPTNPC1RAB9AHTTSMN1; SMN2 | |
| SCHEMBL9557182 | 0.77 | KDM4E (0.51) | MAPT | |
| SCHEMBL9557412 | 0.77 | SMN1; SMN2 (0.42) | NPC1RAB9AL3MBTL1HTTKCNK3 | |
| SCHEMBL9558035 | 0.76 | NPC1 (0.48) | CTSDMAPTNPC1RAB9AKCNK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5225443-A | Lepidotera and Coleoptera insecticides to protect plants | ROHM AND HAAS COMPANY (US) | 1993-07-06 | — | — | US | disclosed |
| EP-0245950-A2 | Insecticidal n-substituted-n' - substituted-n, n'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1987-11-19 | — | — | EP | disclosed |