Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8174989 | 0.87 | POLB (0.50) | HPGDSMN1; SMN2ALDH1A1CYP3A4POLB | |
| SCHEMBL9557546 | 0.86 | TRPV1 (0.49) | HPGDALDH1A1HDAC1HDAC6 | |
| SCHEMBL7878922 | 0.84 | HPGD (0.49) | HPGDSMN1; SMN2ALDH1A1LIMK2HDAC1 | |
| SCHEMBL9557566 | 0.84 | HPGD (0.49) | HPGDSMN1; SMN2ALDH1A1LIMK2HDAC1 | |
| SCHEMBL9557966 | 0.83 | CES2 (0.50) | HPGDSMN1; SMN2ALDH1A1CYP3A4POLB | |
| SCHEMBL9558129 | 0.83 | CES2 (0.47) | HPGDSMN1; SMN2ALDH1A1CYP3A4POLB | |
| SCHEMBL9557283 | 0.83 | CES2 (0.50) | HPGDSMN1; SMN2ALDH1A1CYP3A4POLB | |
| SCHEMBL7878919 | 0.83 | HPGD (0.48) | HPGDSMN1; SMN2ALDH1A1LIMK2HDAC1 | |
| SCHEMBL9557830 | 0.82 | KCNK9 (0.47) | ALDH1A1POLB | |
| SCHEMBL9557428 | 0.82 | RECQL (0.50) | HPGDLIMK2CYP3A4POLBCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5225443-A | Lepidotera and Coleoptera insecticides to protect plants | ROHM AND HAAS COMPANY (US) | 1993-07-06 | — | — | US | disclosed |
| EP-0245950-A2 | Insecticidal n-substituted-n' - substituted-n, n'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1987-11-19 | — | — | EP | disclosed |