Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9557966 | 1.00 | CES2 (0.50) | CES2CES1NPC1RAB9AMEN1 | |
| SCHEMBL9557162 | 0.93 | ALDH1A1 (0.43) | CES2CES1NPC1RAB9AMEN1 | |
| SCHEMBL8174989 | 0.92 | POLB (0.50) | NPC1RAB9AKMT2APOLBALDH1A1 | |
| SCHEMBL9558162 | 0.88 | HPGD (0.48) | HPGDCYP3A4SMN1; SMN2 | |
| SCHEMBL9558223 | 0.88 | ABCB1 (0.48) | MEN1KMT2APOLBCYP3A4 | |
| SCHEMBL9558129 | 0.87 | CES2 (0.47) | CES2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL9557497 | 0.86 | HPGD (0.49) | MEN1KMT2APOLBMAPTHPGD | |
| SCHEMBL9557428 | 0.86 | RECQL (0.50) | NPC1RAB9AMEN1KMT2APOLB | |
| SCHEMBL9557771 | 0.86 | KMT2A (0.41) | CES2CES1MEN1KMT2ALMNA | |
| SCHEMBL9557830 | 0.86 | KCNK9 (0.47) | NPC1RAB9AMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5225443-A | Lepidotera and Coleoptera insecticides to protect plants | ROHM AND HAAS COMPANY (US) | 1993-07-06 | — | — | US | disclosed |
| EP-0245950-A2 | Insecticidal n-substituted-n' - substituted-n, n'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1987-11-19 | — | — | EP | disclosed |