Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.54 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.49 |
| ▸ | CA3 | P07451 | 2/20 | 0.49 |
| ▸ | CA5A | P35218 | 2/20 | 0.49 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 2/20 | 0.49 |
| ▸ | CA4 | P22748 | 1/20 | 0.49 |
| ▸ | CA6 | P23280 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2551625 | 0.83 | TDP1 (0.37) | POLBEPHX1CA12CA2CA9 | |
| SCHEMBL22774011 | 0.83 | TDP1 (0.37) | POLBEPHX1CA12CA2CA9 | |
| SCHEMBL24243979 | 0.82 | SMN1; SMN2 (0.42) | MEN1KMT2AALDH1A1SMN1; SMN2POLB | |
| SCHEMBL3757198 | 0.81 | DUT (0.35) | MEN1KMT2APOLBCA12CA2 | |
| SCHEMBL29750157 | 0.80 | CA14 (0.65) | MEN1KMT2AALDH1A1SMN1; SMN2POLB | |
| SCHEMBL5623734 | 0.80 | MAOA (0.36) | CA12CA2CA9TDP1CA1 | |
| SCHEMBL2877636 | 0.79 | DUT (0.36) | MEN1KMT2AALDH1A1SMN1; SMN2POLB | |
| SCHEMBL29549866 | 0.79 | TDP1 (0.59) | MEN1KMT2APOLBCA12CA2 | |
| SCHEMBL14680159 | 0.79 | TDP1 (0.59) | MEN1KMT2APOLBCA12CA2 | |
| SCHEMBL25773852 | 0.77 | MEN1 (0.70) | MEN1KMT2AALDH1A1SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5210203-A | Sulfonamide-derivative compounds for tagging nucleic acid probes | SISKA DIAGNOSTICS, INC. (US) | 1993-05-11 | — | — | US | disclosed |
| US-5130446-A | Derivatives of fluoroscein or rhodamine | SISKA DIAGNOSTICS, INC. (US) | 1992-07-14 | — | — | US | disclosed |
| EP-0209996-A2 | Nucleic acid probes comprising N4 -(substituted amino)cytidines | SISKA DIAGNOSTICS,INC. (US) | 1987-01-28 | — | — | EP | disclosed |