Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CTSD | P07339 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9557846 | 0.89 | CTSD (0.46) | ALDH1A1SMN1; SMN2MAPTTDP1LMNA | |
| SCHEMBL10779145 | 0.86 | CTSD (0.39) | ALDH1A1MAPTTDP1LMNAHTT | |
| SCHEMBL9558110 | 0.82 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2MAPTTDP1LMNA | |
| SCHEMBL9557722 | 0.76 | TP53 (0.54) | LMNAHTTPOLB | |
| SCHEMBL9714632 | 0.76 | ABCB1 (0.54) | — | |
| SCHEMBL9877030 | 0.76 | ABCB1 (0.54) | — | |
| SCHEMBL9557291 | 0.75 | TP53 (0.38) | ALDH1A1SMN1; SMN2LMNANPC1RAB9A | |
| SCHEMBL9557570 | 0.74 | SLC6A2 (0.45) | — | |
| SCHEMBL9557471 | 0.73 | TSHR (0.43) | ALDH1A1SMN1; SMN2MAPTTDP1LMNA | |
| SCHEMBL9557714 | 0.73 | ABCB1 (0.44) | ALDH1A1SMN1; SMN2NPC1RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5225443-A | Lepidotera and Coleoptera insecticides to protect plants | ROHM AND HAAS COMPANY (US) | 1993-07-06 | — | — | US | disclosed |
| EP-0245950-A2 | Insecticidal n-substituted-n' - substituted-n, n'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1987-11-19 | — | — | EP | disclosed |