Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | PGR | P06401 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | HRH1 | P35367 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MLYCD | O95822 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8174284 | 0.93 | ALDH1A1 (0.46) | ALDH1A1HPGDPGRADRA2AADRA2B | |
| SCHEMBL9557810 | 0.83 | NPC1 (0.42) | ALDH1A1HPGDPGRADRA2AADRA2B | |
| SCHEMBL1003664 | 0.81 | HPGD (0.69) | ALDH1A1HPGDPGRADRA2AADRA2B | |
| SCHEMBL9557674 | 0.79 | ALDH1A1 (0.49) | ALDH1A1HPGDPGRADRA2AADRA2B | |
| SCHEMBL1004360 | 0.78 | MLYCD (0.62) | ALDH1A1HPGDPGRADRA2AADRA2B | |
| SCHEMBL27579062 | 0.78 | ALDH1A1 (0.55) | ALDH1A1HPGDPGRADRA2AADRA2B | |
| SCHEMBL9557549 | 0.77 | ALDH1A1 (0.46) | ALDH1A1HPGDPGRADRA2AADRA2B | |
| SCHEMBL9558054 | 0.77 | ALDH1A1 (0.46) | ALDH1A1HPGDPGRADRA2AADRA2B | |
| SCHEMBL1003650 | 0.77 | NAMPT (0.55) | ALDH1A1HPGDPGRADRA2AADRA2B | |
| SCHEMBL10767577 | 0.75 | ALDH1A1 (0.43) | ALDH1A1HPGDPGRADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5225443-A | Lepidotera and Coleoptera insecticides to protect plants | ROHM AND HAAS COMPANY (US) | 1993-07-06 | — | — | US | disclosed |
| EP-0245950-B1 | INSECTICIDAL N-SUBSTITUTED-N' - SUBSTITUTED-N, N'-DIACYLHYDRAZINES | ROHM AND HAAS COMPANY (US) | 1992-06-17 | — | — | EP | disclosed |
| EP-0245950-A2 | Insecticidal n-substituted-n' - substituted-n, n'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1987-11-19 | — | — | EP | disclosed |