Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | ACE | P12821 | 3/20 | 0.51 |
| ▸ | YAP1 | P46937 | 2/20 | 0.50 |
| ▸ | CMA1 | P23946 | 3/20 | 0.48 |
| ▸ | ATM | Q13315 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9558236 | 0.85 | MAPK1 (0.64) | MAPK1KMT2AACEYAP1ATM | |
| SCHEMBL9558142 | 0.81 | MAPK1 (0.55) | MAPK1ALDH1A1HSD17B10KMT2AACE | |
| SCHEMBL21748404 | 0.79 | CMA1 (0.63) | MAPK1ALDH1A1HSD17B10KMT2AACE | |
| SCHEMBL3165695 | 0.79 | CMA1 (0.63) | MAPK1ALDH1A1HSD17B10KMT2AACE | |
| SCHEMBL3165688 | 0.79 | CMA1 (0.63) | MAPK1ALDH1A1HSD17B10KMT2AACE | |
| SCHEMBL3825215 | 0.79 | CMA1 (0.63) | MAPK1ALDH1A1HSD17B10KMT2AACE | |
| SCHEMBL9051863 | 0.78 | MAPK1 (0.58) | MAPK1ALDH1A1HSD17B10KMT2AACE | |
| SCHEMBL25997791 | 0.77 | ATM (0.50) | ALDH1A1HSD17B10ACEYAP1ATM | |
| SCHEMBL25999013 | 0.77 | ATM (0.50) | ALDH1A1HSD17B10ACEYAP1ATM | |
| SCHEMBL25998975 | 0.77 | ATM (0.50) | ALDH1A1HSD17B10ACEYAP1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5215968-A | Hypotension agents and viricides | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-06-01 | — | — | US | disclosed |
| EP-0373497-A2 | Dipeptide derivatives with an enzyme-inhibiting activity | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-06-20 | — | — | EP | disclosed |