Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.64 |
| ▸ | YAP1 | P46937 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.56 |
| ▸ | ACE | P12821 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.49 |
| ▸ | STS | P08842 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22834245 | 0.86 | MAPK1 (0.64) | MAPK1YAP1KMT2AGPR119MEN1 | |
| SCHEMBL22834248 | 0.86 | MAPK1 (0.64) | MAPK1YAP1KMT2AGPR119MEN1 | |
| SCHEMBL9558140 | 0.85 | MAPK1 (0.58) | MAPK1YAP1KMT2AACEATM | |
| SCHEMBL6165579 | 0.84 | MAPK1 (0.75) | MAPK1YAP1KMT2AATMMEN1 | |
| SCHEMBL6165580 | 0.84 | MAPK1 (0.75) | MAPK1YAP1KMT2AATMMEN1 | |
| SCHEMBL9558243 | 0.83 | YAP1 (0.64) | MAPK1YAP1KMT2AACEATM | |
| SCHEMBL7276592 | 0.81 | POLB (0.65) | MAPK1YAP1KMT2AACEPOLB | |
| SCHEMBL7276597 | 0.81 | POLB (0.65) | MAPK1YAP1KMT2AACEPOLB | |
| SCHEMBL22834076 | 0.81 | MAPK1 (0.58) | MAPK1YAP1KMT2AGPR119MEN1 | |
| SCHEMBL22834077 | 0.81 | MAPK1 (0.58) | MAPK1YAP1KMT2AGPR119MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5215968-A | Hypotension agents and viricides | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-06-01 | — | — | US | disclosed |
| EP-0373497-A2 | Dipeptide derivatives with an enzyme-inhibiting activity | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-06-20 | — | — | EP | disclosed |