Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 15/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.39 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.37 |
| ▸ | CYP26B1 | Q9NR63 | 2/20 | 0.37 |
| ▸ | RXRB | P28702 | 4/20 | 0.37 |
| ▸ | RXRG | P48443 | 3/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | RARB | P10826 | 1/20 | 0.36 |
| ▸ | RARG | P13631 | 1/20 | 0.36 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL36554 | 0.81 | ESR2 (0.45) | OPRM1 | |
| SCHEMBL10528665 | 0.78 | LIG1 (0.41) | OPRM1 | |
| SCHEMBL1248050 | 0.78 | KDM1A (0.44) | — | |
| SCHEMBL9557833 | 0.74 | CYP3A4 (0.33) | — | |
| SCHEMBL29119962 | 0.72 | RXRA (0.49) | RXRANR4A2SRD5A2CYP26A1CYP26B1 | |
| SCHEMBL15225013 | 0.71 | POLA1 (0.32) | KMT2A | |
| SCHEMBL418997 | 0.71 | RARB (0.50) | RXRANR4A2CYP26A1CYP26B1RXRB | |
| Diethylamine SCHEMBL11098173 | 0.70 | KDM1A (0.40) | — | |
| SCHEMBL16861453 | 0.69 | TP53 (0.44) | RXRASRD5A2CYP26A1CYP26B1RXRB | |
| SCHEMBL12356799 | 0.69 | RXRA (0.49) | RXRASRD5A2CYP26A1CYP26B1RXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0332425-B1 | PROCESS FOR REFINING 1,3-DIMETHYL-2-IMIDAZOLIDINONE AND A PROCESS FOR PREPARING AN AROMATIC POLYAMIDE BY USE OF THE REFINED PRODUCT | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1993-01-27 | — | — | EP | disclosed |
| US-5075406-A | Solution polymerization of polyamides in solvent purified by adsorption on magnesia, alumina, silica or mixed oxides | MITSUI TOATSU CHEMICALS, INC. (JP) | 1991-12-24 | — | — | US | disclosed |
| US-5011936-A | Using composite salt consisting of at least two of silica, magnesia and alumina | MITSUI TOATSU CHEMICALS, INC. (JP) | 1991-04-30 | — | — | US | disclosed |
| US-4923951-A | DIISOCYANTE, ALKALI OR ALKALINE EARTH METAL CATALYST | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1990-05-08 | — | — | US | disclosed |
| EP-0332425-A1 | Process for refining 1,3-dimethyl-2-imidazolidinone and a process for preparing an aromatic polyamide by use of the refined product | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1989-09-13 | — | — | EP | disclosed |
| EP-0328342-A2 | Process for producing aromatic polyamides | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1989-08-16 | — | — | EP | disclosed |