Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 6/20 | 0.50 |
| ▸ | RARG | P13631 | 6/20 | 0.50 |
| ▸ | RARA | P10276 | 4/20 | 0.50 |
| ▸ | RXRA | P19793 | 14/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.44 |
| ▸ | CYP26B1 | Q9NR63 | 2/20 | 0.44 |
| ▸ | RXRB | P28702 | 5/20 | 0.44 |
| ▸ | RXRG | P48443 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29119962 | 0.98 | RXRA (0.49) | RARBRARGRARARXRATP53 | |
| SCHEMBL12356799 | 0.94 | RXRA (0.49) | RARBRARGRARARXRATP53 | |
| SCHEMBL15956227 | 0.90 | TP53 (0.52) | RARBRARGRARARXRATP53 | |
| SCHEMBL611940 | 0.86 | ALDH1A1 (0.41) | RARBRARGRARARXRARXRB | |
| SCHEMBL29119959 | 0.83 | ALDH1A1 (0.40) | RARBRARGRARAALDH1A1 | |
| Terephthalic Acid SCHEMBL2790074 | 0.82 | TP53 (0.52) | RARBRARGRARARXRATP53 | |
| SCHEMBL10602015 | 0.81 | ESR1 (0.42) | ALDH1A1 | |
| SCHEMBL29119934 | 0.81 | ALDH1A1 (0.41) | RARBRARGRARARXRAALDH1A1 | |
| SCHEMBL14667564 | 0.80 | CA1 (0.48) | TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL8724310 | 0.80 | HSD11B1 (0.38) | RARBRARGRARASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115724736-A | Carboxylic acid, acyl chloride compound, carbazole group-containing compound, oxime ester photoinitiator, photocuring coating and cured film | 阜阳欣奕华材料科技有限公司 | 2023-03-03 | — | — | CN | disclosed |
| EP-2607348-B1 | Plasminogen Activator Inhibitor-1 Inhibitor | RENASCIENCE INC (JP) | 2021-03-17 | — | — | EP | disclosed |
| CN-102378753-B | Plasminogen activator-1 inhibitor | RENASCIENCE Co.,Ltd. (JP) | 2016-03-02 | — | — | CN | disclosed |
| US-20140296256-A1 | PLASMINOGEN ACTIVATOR INHIBITOR-1 INHIBITOR | RENASCIENCE CO LTD (JP) | 2014-10-02 | — | — | US | disclosed |
| US-8785473-B2 | Plasminogen activator inhibitor-1 inhibitor | RENASCIENCE CO., LTD. (JP) | 2014-07-22 | — | — | US | disclosed |
| EP-2607348-A2 | Plasminogen Activator Inhibitor-1 Inhibitor | Renascience CO., LTD. (JP) | 2013-06-26 | — | — | EP | disclosed |
| CN-102378753-A | Plasminogen activator inhibitor-1 inhibitor | RENASCIENCE CO LTD | 2012-03-14 | — | — | CN | disclosed |
| EP-2415755-A1 | PLASMINOGEN ACTIVATOR INHIBITOR-1 INHIBITOR | Renascience CO., LTD. (JP) | 2012-02-08 | — | — | EP | disclosed |
| US-20120022080-A1 | Plasminogen Activator Inhibitor-1 Inhibitor | RENASCIENCE CO., LTD. (JP) | 2012-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140296256-A1 | PLASMINOGEN ACTIVATOR INHIBITOR-1 INHIBITOR | SERPINE1, SERPINC1, SERPINB1 | RARB 3998/4885RARG 4240/4885RARA 3862/4885 |
| US-20120022080-A1 | Plasminogen Activator Inhibitor-1 Inhibitor | SERPINE1, SERPINC1, SERPINB1 | RARB 3998/4885RARG 4240/4885RARA 3862/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.