SCHEMBL9558206

SCHEMBL9558206

CC(C)(CCCc1cccc(Oc2ccccc2)c1)c1ccc2c(c1)OCO2

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 5/20 0.47
MAOA P21397 3/20 0.47
HTR2A P28223 5/20 0.43
HTR2C P28335 5/20 0.43
HTR2B P41595 5/20 0.43
CALM1 P0DP23 3/20 0.43
FDFT1 P37268 2/20 0.42
ADRB1 P08588 1/20 0.41
HTR1A P08908 1/20 0.41
ADRA2A P08913 1/20 0.41
DRD2 P14416 1/20 0.41
ADRA2B P18089 1/20 0.41
ADRA2C P18825 1/20 0.41
DRD1 P21728 1/20 0.41
DRD4 P21917 1/20 0.41
SLC6A2 P23975 1/20 0.41
ADRA1D P25100 1/20 0.41
HTR1D P28221 1/20 0.41
SLC6A4 P31645 1/20 0.41
HTR7 P34969 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10650475 0.86 MAOB (0.43) MAOBMAOAHTR2AHTR2CHTR2B
SCHEMBL10649069 0.86 MAOB (0.43) MAOBMAOAHTR2AHTR2CHTR2B
SCHEMBL10546789 0.84 HTR2A (0.42) MAOBMAOAHTR2AHTR2CHTR2B
SCHEMBL10548261 0.83 FDFT1 (0.48) FDFT1ALDH1A1SMN1; SMN2
SCHEMBL9558346 0.83 MAOB (0.45) MAOBMAOACALM1FAAHALDH1A1
SCHEMBL10649512 0.83 MAOB (0.42) MAOBMAOAHTR2AHTR2CHTR2B
SCHEMBL10646817 0.83 MAOB (0.42) MAOBMAOAHTR2AHTR2CHTR2B
SCHEMBL10652038 0.82 MAOB (0.41) MAOBMAOAHTR2AHTR2CHTR2B
SCHEMBL10656719 0.82 MAOB (0.41) MAOBMAOAHTR2AHTR2CHTR2B
SCHEMBL9558181 0.82 FDFT1 (0.48) FDFT1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0257415-B1 INSECTICIDAL RESIN COATING FILM MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-03-31 EP disclosed
US-4997650-A (Meth)acrylonitrile polymer MITSUI TOATSU CHEMICALS, INC. (JP) 1991-03-05 US disclosed
US-4818525-A LONG-LASTING; ACRYLONITRILE COPOLYMER MITSUI TOATSU CHEMICALS, INC. (JP) 1989-04-04 US disclosed
US-4814340-A 1,4-diaryl alkane derivatives having insecticidal and acaricidal activity MITSUI TOATSU CHEMICALS, INC. (JP) 1989-03-21 US disclosed
EP-0257415-A1 Insecticidal resin coating film MITSUI TOATSU CHEMICALS, Inc. (JP) 1988-03-02 EP disclosed
US-4661501-A Certain aryl-alkane-2-pyridyloxy-phenyl derivatives having insecticidal and acaricidal activity MITSUI TOATSU CHEMICALS, INC. (JP) 1987-04-28 US disclosed