Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.41 |
| ▸ | MAOA | P21397 | 3/20 | 0.41 |
| ▸ | HTR2A | P28223 | 5/20 | 0.38 |
| ▸ | HTR2C | P28335 | 5/20 | 0.38 |
| ▸ | HTR2B | P41595 | 5/20 | 0.38 |
| ▸ | CALM1 | P0DP23 | 2/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10649512 | 0.93 | MAOB (0.42) | MAOBMAOAHTR2AHTR2CHTR2B | |
| SCHEMBL10648084 | 0.87 | HTR2A (0.37) | MAOBMAOAHTR2AHTR2CHTR2B | |
| SCHEMBL10650475 | 0.85 | MAOB (0.43) | MAOBMAOAHTR2AHTR2CHTR2B | |
| SCHEMBL10654368 | 0.84 | NOS2 (0.38) | MAOBMAOAALDH1A1GAA | |
| SCHEMBL10648044 | 0.82 | FDFT1 (0.44) | FDFT1TSHRHSD17B10ALDH1A1KDM4E | |
| SCHEMBL10647349 | 0.82 | ALDH1A1 (0.40) | FDFT1TSHRHSD17B10ALDH1A1KDM4E | |
| SCHEMBL9558206 | 0.82 | MAOB (0.47) | MAOBMAOAHTR2AHTR2CHTR2B | |
| SCHEMBL10648019 | 0.81 | LTA4H (0.44) | FDFT1TSHRHSD17B10 | |
| SCHEMBL10652038 | 0.81 | MAOB (0.41) | MAOBMAOAHTR2AHTR2CHTR2B | |
| SCHEMBL10651174 | 0.81 | HTR2A (0.38) | MAOBMAOAHTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4772633-A | 6-pyridyl- and 6-phenyl-3-phenyl-1-hexenes and -1-hexynes, composition containing them, and insecticidal and acaricidal method of using them | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1988-09-20 | — | — | US | disclosed |
| EP-0193189-A1 | Novel compound, its production and insecticidal and acaricidal composition containing it as an active ingredient | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1986-09-03 | — | — | EP | disclosed |