Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 3/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | MAP1LC3B | Q9GZQ8 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3142596 | 0.95 | SMN1; SMN2 (0.52) | SMN1; SMN2L3MBTL1POLBTP53CTDSP1 | |
| SCHEMBL21635879 | 0.93 | SMN1; SMN2 (0.50) | SMN1; SMN2L3MBTL1POLBTP53CTDSP1 | |
| SCHEMBL6837311 | 0.90 | MAP1LC3B (0.47) | SMN1; SMN2L3MBTL1POLBTP53CTDSP1 | |
| SCHEMBL24933630 | 0.78 | MAP1LC3B (0.43) | SMN1; SMN2L3MBTL1POLBTP53CTDSP1 | |
| SCHEMBL1310728 | 0.78 | SMN1; SMN2 (0.45) | SMN1; SMN2L3MBTL1POLBTP53CTDSP1 | |
| SCHEMBL1310726 | 0.78 | SMN1; SMN2 (0.45) | SMN1; SMN2L3MBTL1POLBTP53CTDSP1 | |
| SCHEMBL12110722 | 0.78 | SMN1; SMN2 (0.45) | SMN1; SMN2L3MBTL1POLBTP53CTDSP1 | |
| SCHEMBL3588788 | 0.73 | SMN1; SMN2 (0.47) | SMN1; SMN2L3MBTL1POLBTP53CTDSP1 | |
| SCHEMBL2727810 | 0.73 | SMN1; SMN2 (0.47) | SMN1; SMN2L3MBTL1POLBTP53CTDSP1 | |
| SCHEMBL2727811 | 0.73 | SMN1; SMN2 (0.47) | SMN1; SMN2L3MBTL1POLBTP53CTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 236 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4055016-B1 | GPR52 MODULATOR COMPOUNDS | NXERA PHARMA UK LTD (GB) | 2026-04-29 | — | — | EP | disclosed |
| EP-4536655-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS OF USING THEREOF | Sionna Therapeutics Inc. (US) | 2025-04-16 | — | — | EP | disclosed |
| CN-119677730-A | Compounds, compositions, and methods of use thereof | 希安纳医疗公司 | 2025-03-21 | — | — | CN | disclosed |
| CN-119585247-A | Bicyclic heterocyclic amide inhibitors of nav1.8 for the treatment of pain | 赛特温治疗公司 | 2025-03-07 | — | — | CN | disclosed |
| EP-4514789-A1 | <SUP2/>? <SUB2/>?V?BICYCLIC HETEROCYCLIC AMIDE INHIBITORS OF NA1.8 FOR THE TREATMENT OF PAIN | SiteOne Therapeutics, Inc. (US) | 2025-03-05 | — | — | EP | disclosed |
| CN-118598868-A | GPR52 modulator compound | 江苏海洋大学 | 2024-09-06 | — | — | CN | disclosed |
| WO-2023240267-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS OF USING THEREOF | SIONNA THERAPEUTICS (US) | 2023-12-14 | — | — | WO | disclosed |
| WO-2023240267-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS OF USING THEREOF | SIONNA THERAPEUTICS (US) | 2023-12-14 | — | — | WO | disclosed |
| US-20230348401-A1 | Inhibitors of Glucose-6-phosphate Dehydrogenase and Uses Thereof | THE TRUSTEES OF PRINCETON UNIVERSITY | 2023-11-02 | — | — | US | disclosed |
| US-20230348401-A1 | Inhibitors of Glucose-6-phosphate Dehydrogenase and Uses Thereof | THE TRUSTEES OF PRINCETON UNIVERSITY | 2023-11-02 | — | — | US | disclosed |
| US-5068334-A | Analgesics and antipyretics | KARL THOMAE GMBH (DE) | 1991-11-26 | — | — | US | disclosed |
| EP-0192783-B1 | 2-PIPERAZINOPYRIMIDINE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1991-04-17 | — | — | EP | disclosed |
| EP-0276833-A2 | Dipyrazoles useful as bronchodilators | MERRELL DOW PHARMACEUTICALS INC. (US) | 1988-08-03 | — | — | EP | disclosed |
| EP-0276834-A1 | Cycloalkane [1,2-c:4,3-c'] dipyrazoles | MERRELL DOW PHARMACEUTICALS INC. (US) | 1988-08-03 | — | — | EP | disclosed |
| US-4742165-A | HERBICIDES | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1988-05-03 | — | — | US | disclosed |
| US-4734430-A | Dipyrazoles and their use as bronchodilators | MERRELL DOW PHARMACEUTICALS INC. (US) | 1988-03-29 | — | — | US | disclosed |
| US-4734429-A | Cycloalkane[1,2-c:4,3-c']dipyrazoles and their use as bronchodilators | MERRELL DOW PHARMACEUTICALS INC. (US) | 1988-03-29 | — | — | US | disclosed |
| US-4734418-A | Quinazoline compounds and antihypertensives | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1988-03-29 | — | — | US | disclosed |
| EP-0192783-A1 | 2-PIPERAZINOPYRIMIDINE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1986-09-03 | — | — | EP | disclosed |
| EP-0188094-A2 | Quinazoline derivatives and antihypertensive preparations containing same as effective components | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1986-07-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230348401-A1 | Inhibitors of Glucose-6-phosphate Dehydrogenase and Uses Thereof | G6PD, UGDH, GPI | SMN1; SMN2 4412/4885L3MBTL1 3320/4885POLB 1899/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.