SCHEMBL9558552

SCHEMBL9558552

CCCCCN(CC(=O)N1CCCCC1)C(=O)C(CCC(=O)O)CS(=O)(=O)c1ccc2ccccc2c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.49
HTT P42858 3/20 0.49
CCKBR P32239 6/20 0.43
MAPT P10636 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
MEN1 O00255 2/20 0.40
RAB9A P51151 2/20 0.40
KMT2A Q03164 2/20 0.40
MITF O75030 1/20 0.40
LMNA P02545 2/20 0.39
HSD17B10 Q99714 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
PLA2G1B P04054 1/20 0.38
ATG4B Q9Y4P1 1/20 0.38
PKM P14618 2/20 0.38
GAA P10253 1/20 0.38
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
MMP1 P03956 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9558492 0.91 ALDH1A1 (0.47) ALDH1A1HTTCCKBRMAPTSMN1; SMN2
SCHEMBL9559135 0.83 GAA (0.49) ALDH1A1CCKBRGAACA12CA1
SCHEMBL9558862 0.81 CCKBR (0.51) ALDH1A1CCKBRMMP1MMP7ACE
SCHEMBL9559024 0.80 CCKBR (0.46) ALDH1A1CCKBRGAACA12CA1
Water SCHEMBL9559012 0.80 CCKBR (0.50) ALDH1A1CCKBRMMP1MMP7ACE
SCHEMBL9558893 0.80 CCKBR (0.47) ALDH1A1CCKBRGAACA12CA1
SCHEMBL9558525 0.76 ALDH1A1 (0.43) ALDH1A1HTTCCKBRSMN1; SMN2RAB9A
SCHEMBL9559158 0.76 GAA (0.48) ALDH1A1HTTCCKBRSMN1; SMN2MEN1
SCHEMBL9558853 0.75 ALDH1A1 (0.43) ALDH1A1HTTCCKBRSMN1; SMN2RAB9A
SCHEMBL9559037 0.75 GAA (0.46) ALDH1A1CCKBRMEN1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5177069-A Cholecystokinin inhibitor, pancreatic antisecretory agent KISSEI PHARMACEUTICAL CO., LTD. (JP) 1993-01-05 US disclosed
EP-0433064-A1 Naphthylsulfonylalkanoic acid compounds Kissei Pharmaceutical Co., Ltd. (JP) 1991-06-19 EP disclosed