Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.57 |
| ▸ | PPARA | Q07869 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | RXRA | P19793 | 3/20 | 0.50 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.49 |
| ▸ | CFD | P00746 | 1/20 | 0.49 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA4 | P22748 | 1/20 | 0.49 |
| ▸ | CA6 | P23280 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | TPMT | P51580 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | RXRB | P28702 | 1/20 | 0.48 |
| ▸ | RXRG | P48443 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6866012 | 0.92 | PPARG (0.65) | PPARGPPARAALDH1A1CFDCA2 | |
| SCHEMBL3721241 | 0.89 | PPARG (0.58) | PPARGPPARAALDH1A1CFDCA2 | |
| SCHEMBL966378 | 0.81 | CA12 (0.71) | ALDH1A1CA2CA12CA1CA4 | |
| SCHEMBL19413941 | 0.80 | SRD5A2 (0.59) | ALDH1A1RXRANR1H4CFDSRD5A2 | |
| SCHEMBL5501065 | 0.80 | PPARG (0.68) | PPARGPPARAALDH1A1TSHRHTT | |
| SCHEMBL3914968 | 0.80 | PPARG (0.63) | PPARGPPARAALDH1A1TSHRHTT | |
| SCHEMBL6866417 | 0.80 | KLKB1 (0.58) | ALDH1A1RXRACFDSRD5A2CA2 | |
| Hydrochloric Acid SCHEMBL17667160 | 0.80 | CA12 (0.69) | PPARGPPARAALDH1A1CA2CA12 | |
| SCHEMBL2772851 | 0.79 | GAA (0.68) | PPARGPPARAALDH1A1NR1H4TSHR | |
| SCHEMBL8960746 | 0.79 | PDE4A (0.57) | ALDH1A1RXRACA2CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0332425-B1 | PROCESS FOR REFINING 1,3-DIMETHYL-2-IMIDAZOLIDINONE AND A PROCESS FOR PREPARING AN AROMATIC POLYAMIDE BY USE OF THE REFINED PRODUCT | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1993-01-27 | — | — | EP | disclosed |
| US-5075406-A | Solution polymerization of polyamides in solvent purified by adsorption on magnesia, alumina, silica or mixed oxides | MITSUI TOATSU CHEMICALS, INC. (JP) | 1991-12-24 | — | — | US | disclosed |
| US-5011936-A | Using composite salt consisting of at least two of silica, magnesia and alumina | MITSUI TOATSU CHEMICALS, INC. (JP) | 1991-04-30 | — | — | US | disclosed |
| US-4923951-A | DIISOCYANTE, ALKALI OR ALKALINE EARTH METAL CATALYST | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1990-05-08 | — | — | US | disclosed |
| EP-0332425-A1 | Process for refining 1,3-dimethyl-2-imidazolidinone and a process for preparing an aromatic polyamide by use of the refined product | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1989-09-13 | — | — | EP | disclosed |
| EP-0328342-A2 | Process for producing aromatic polyamides | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1989-08-16 | — | — | EP | disclosed |