Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.58 |
| ▸ | PPARA | Q07869 | 1/20 | 0.58 |
| ▸ | HNF4A | P41235 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | CFD | P00746 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.49 |
| ▸ | MPO | P05164 | 1/20 | 0.48 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.47 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.46 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.46 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6866012 | 0.93 | PPARG (0.65) | PPARGPPARAHNF4AALDH1A1KDM4E | |
| SCHEMBL9558573 | 0.89 | PPARG (0.57) | PPARGPPARAALDH1A1CFDCA2 | |
| SCHEMBL3914968 | 0.81 | PPARG (0.63) | PPARGPPARAALDH1A1KDM4EHPGD | |
| SCHEMBL5501065 | 0.81 | PPARG (0.68) | PPARGPPARAALDH1A1KDM4EHPGD | |
| SCHEMBL2772851 | 0.80 | GAA (0.68) | PPARGPPARAALDH1A1KDM4EHPGD | |
| SCHEMBL506455 | 0.80 | PPARG (0.61) | PPARGPPARAALDH1A1KDM4EHPGD | |
| SCHEMBL6866159 | 0.80 | CFD (0.70) | PPARGPPARAHNF4AALDH1A1KDM4E | |
| SCHEMBL83495 | 0.79 | CA2 (0.80) | PPARGPPARAALDH1A1KDM4ECA2 | |
| SCHEMBL4521510 | 0.79 | HNF4A (0.73) | HNF4AALDH1A1CFDMPOACMSD | |
| SCHEMBL3963370 | 0.79 | PPARA (0.78) | PPARGPPARAALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010100475-A1 | HYDROXAMIC ACID DERIVATIVES AS GRAM-NEGATIVE ANTIBACTERIAL AGENTS | ASTRAZENECA AB (SE) | 2010-09-10 | — | — | WO | disclosed |